Publications

Found 36 results

2022
Tsika AC, Gallo A, Fourkiotis NK, Argyriou AI, Sreeramulu S, Löhr F, Rogov VV, Richter C, Linard V, Gande SL et al..  2022.  Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. J. Mol. Biol.. 434(16):167720.
Landgraf T, Völklein AE, Fürtig* B, Schwalbe* H.  2022.  The cotranscriptional folding landscape for two cyclic di-nucleotide-sensing riboswitches with highly homologous aptamer domains acting either as ON- or OFF-switches. Nucl. Acids Res. 50(12):6639-55.
Leisegang MS, Bains KJ, Seredinski S, Oo LA, Krause NM, Kuo C-C, Günther S, Cetin NS, Warwick T, Cao C et al..  2022.  HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nat. Commun. 13( 6563)
Heering J, Jores N, Kilu W, Schallmayer E, Peelen E, Muehler A, Kohlhof H, Vitt D, Linhard V, Gande SL et al..  2022.  Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators . ACS CHem. Biol..
Schweizer-Stenner* R, Milorey B, Schwalbe* H.  2022.  Randomizing of oligopeptide conformations by nearest neighbor interactions between amino acids. Biomolecules. 12:684.
Blümler A, Schwalbe* H, Heckel* A.  2022.  Solid-Phase-Supported Chemoenzymatic Synthesis of a Light-Activatable tRNA Derivative.. Angew. Chem. Intl. Ed.. 61:e202111613.
Broft P, Rosenkranz R, Schleiff E, Hengesbach* M, Schwalbe* H.  2022.  Structural analysis of temperature-dependent alternative splicing of HsfA2 pre-mRNA from tomato plants. RNA Biology. 19:266-278.
2021
Richter C, K. F. Hohmann, S. Toews MADN, Toews S, Mathieu D, Altincekic N, Bains KJ, Binas O, Ceylan B, Duchardt-Ferner E, Ferner J et al..  2021.  1H, 13C, and 15N Assignment of Stem-Loop SL1 from the 5'-UTR of SARS-CoV-2. Biomolecular NMR assignments. 15(2):467-474.
Qureshi N, Matzel T, Cetiner E, Schnieders R, Jonker HRA, Schwalbe* H, Fürtig B.  2021.  NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs.. Nucl. Acids Res. 49(13):7753-7764.
Radloff M, Elamri I, Grund TN, Witte LF, Nakagaki S, Goojani HG, Nasiri H, Miyoshi H, Bald D, Xie H et al..  2021.  Short - chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd I and bd-II oxidases. Sci. Rep..
Radloff M, Elamri I, Grund TN, Witte LF, Hohmann KF, Nagagaki S, Goojani HG, Nasiri H, Hideto M, Bald D et al..  2021.  Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II. Sci. Rep.. 11:23852.
2020
Novakovic M, Olsen GL, Pinter G, Hymon D, Fürtig B, Schwalbe* H, Frydman* L.  2020.  A 300-fold enhancement of imino nucleic acid resonances by hyperpolarized water: A new window for probing RNA refolding by 1D and 2D NMR.. Proc. Natl. Acad. Sci. USA. 117(5):2449-2455.
Binas O, de Jesus V, Landgraf T, Völklein AE, Martins J, Hymon D, Bains KJ, Berg H, Biedenbänder T, Fürtig B et al..  2020.  19F-NMR-based fragment screening for 14 different biologically active RNAs and 10 DNA and protein counter-screens. ChemBioChem.
Cantini F, Banci* L, Altincekic N, Bains JK, Dhamotharan K, Fuks C, Fürtig B, Gande SL, Hargittay B, Hengesbach M et al..  2020.  1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP‑ribose bound forms of the macrodomain of SARS‑CoV‑2 non‑structural protein 3b. Biomolecular NMR assignments. 14(2):339-346.
Grün JT, Hennecker C, Klötzner D-P, Harkness R, Bessi I, Heckel A, Mittermaier* A, Schwalbe* H.  2020.  Conformational Dynamics of Strand Register Shifts in DNA G-quadruplexes. J. Am. Chem. Soc.. 142(1):264-273.
Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hordinau VV, Meier-Credo J, Saxena K, Buhr F, Langer JD et al..  2020.  Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nat Commun. . 11(1):5569.
Broft P, Dzatko S, Krafcikova M, Hansel-Hertsch R, Wacker A, Doetsch V, Trantirek* L, Schwalbe* H.  2020.  In-cell NMR of functional riboswitch aptamers in eukaryotic cells. Angew. Chem. Int. Ed. Engl..
Kubatova N, Mao J, Eckert CE, Saxena K, Gande SL, Wachtveitl* J, Glaubitz* C, Schwalbe* H.  2020.  Light dynamics of retinal disease-relevant G90D bovine rhodopsin mutant. Angew. Chem. Int. Ed. Engl.. 59:15656–15664.
Heiliger J, Matzel T, Cetiner EC, Schwalbe* H, Kuenze* G, Corzilius B.  2020.  Site-specific dynamic nuclear polarization in a Gd(III)-labeled protein. Chem. Phys. Phys. Chem..
2019
Merk* D, Sreeramulu S, Kudlinzki D, Saxena K, Linhardt V, Gande SL, Hiller F, Lamers C, Nilsson E, Aagard A et al..  2019.  Molecular tuning of farnesoid X receptor partial agonism. Nature Comm.. 10(1):2915.
Schnieders R, Keyhani S, Schwalbe* H, Fürtig* B.  2019.  More than Proton Detection – New Avenues for NMR of RNA. Chemistry. 26(1):102-111.
Schnieders R, Wolter AC, Richter C, Wöhnert J, Schwalbe* H, Fürtig* B.  2019.  Novel 13C-detected NMR experiments for precise detection of RNA structure. Angew. Chem. Int. Ed.. 58(27):9140-9144.
Kubatova N, Pyper DJ, Jonker HRA, Saxena K, Remmel L, Richter C, Brantl S, Evguenieva-Hackenberg E, Hess W, Klug G et al..  2019.  Rapid biophysical characterization and NMR structural analysis ofsmall proteins from bacteria and archaea. ChemBioChem.
2018
Keyhani S, Goldau T, Blümler A, Heckel* A, Schwalbe* H.  2018.  Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy. Angew. Chem. Int. Ed.. 57:12017-12021.
Qureshi NS, Sreeramulu S, Bains JK, Schwalbe* H, Fürtig* B.  2018.  Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation. Nucl. Acids Res.. 46:10917-10929.
Tröster A, Heinzlmeir S, Berger BT, Gande SL, Saxena K, Sreeramulu S, Linhard V, Nasiri AH, Bolte M, Müller S et al..  2018.  NVP-BHG712: Effects of regioisomers on the affinity and selectivity towards the EPHrin family. ChemMedChem. 13:2358-2464.
Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker HRA, Stelzl L, Hummer G, Schwalbe* H et al..  2018.  Optimal destabilization of DNA double strands by single-nucleobase caging. Chemistry. 24:17568-17576.
Wienen-Schmidt B, Jonker HRA, Wulsdorf T, Gerber H-D, Saxena K, Kudlinzki D, Sreeramulu S, Parigi G, Luchinat C, Heine A et al..  2018.  Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding. J. Med. Chem.. 61:5922-5933.
2017
Lehner F, Kudlinzki D, Richter C, Müller-Werkmeister H, Eberl K, Bredenbeck J, Schwalbe* H, Silvers* R.  2017.  The Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. ChemBioChem. 18:2340-2350.
Herzig' L-M, Elamri' I, Schwalbe* H, Wachtveitl* J.  2017.  Light-induced antibiotic release from a coumarin-caged compound on the ultrafast timescale. Phys Chem Chem Phys. 19(22):14835-14844.
Wirmer-Bartoschek J, Bendel LE, Jonker HRA, Grün JT, Papi F, Bazzicalupi C, Messori L, Gratteri* P, Schwalbe* H.  2017.  The NMR solution structure of a ligand/hybrid-2-G-quadruplex complex reveals structural rearrangements that facilitate ligand binding. Angew. Chem. Intl. Ed.. 56:7102-7106.
Steinert' H, Sochor' F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm S, Rudolph MM et al..  2017.  Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation. eLife. :e21297.
2016
Heinzlmeir# S, Kudlinzki# D, Sreeramulu S, Klaeger S, Gande SL, Linhardt V, Wilhelm M, Qiao H, Helm D, Ruprecht B et al..  2016.  Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs.. ACS Chem. Biol..
Thevarpadam' J, Bessi' I, Binas' O, Schmidt DG, Slavov C, Jonker HRA, Wachtveitl J, Schwalbe* H, Heckel* A.  2016.  Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif. Angew. Chem. Int. Ed.. 55(8):2738-42.
Buhr F, Jha S, Thommen M, Mittelstaet J, Kutz F, Schwalbe* H, Rodnina* M, Komar* A.  2016.  Synonymous codons direct co-translational folding towards different proteins conformations. Mol. Cell. 61(3):341-51.
2013
Herbert C, Schieborr U, Saxena K, Juraszek J, Smet DF, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D et al..  2013.  Molecular mechanism of SSR128129E, an extracellularly acting, small molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell . 23:489-501.