Directed TOCSY, a method for selection of directed correlations by optimal combinations of isotropic and longitudinal mixing.
Title | Directed TOCSY, a method for selection of directed correlations by optimal combinations of isotropic and longitudinal mixing. |
Publication Type | Journal Article |
Year of Publication | 1996 |
Authors | Glaser SJ, Schwalbe H, Marino JP, Griesinger C |
Journal | J Magn Reson B |
Volume | 112 |
Pagination | 160–180 |
Date Published | Aug |
Accession Number | 25 |
Abstract | The directed TOCSY pulse sequence element transfers coherence predominantly into "forward-directed" antiphase coherences while simultaneously suppressing in-phase and "backward-directed" antiphase coherences. This novel selection principle, based on the "direction" of the target coherences, provides a new approach for the simplification of crowded spectra. In this article, the theory of directed TOCSY is presented for linear spin systems that are frequently found in carbon-labeled biomolecules. |