Publications

Found 466 results

2023
Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Richter C, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J et al..  2023.  COVID19-NMR consortium: A public report on the impact of this new global collaboration. Angew. Chem. Intl. Ed.. :e202217171.
Li Y, Pustovalova Y, Shi W, Gorbatyuk O, Sreeramulu S, Schwalbe H, Hoch JC, Hao B.  2023.  Crystal structure of the CoV-Y domain of SARS-CoV-2 nonstructural protein 3.. Sci Rep.. 13(1):2890.
Grün JT, Kim J, Jayanthi S, Lupulescu A, Kupče ER, Schwalbe H, Frydman L.  2023.  Identifying and Overcoming Artifacts in 1H-Based Saturation Transfer NOE NMR Experiments. J. Am. Chem. Soc..
Cherepanov AV, Schwalbe H.  2023.  Large Temperature-Jump and Nanosecond Hyperquenching for Time-Resolve Structural Studies. Chemistry Method.
Kunert S, Linhard V, Weidrich S, Choudalakis M, Osswald F, Krämer L, Köhler AR, Bröhm A, Wollenhaupt J, Schwalbe H et al..  2023.  The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site. Protein Sci. 32(1):e4542.
Hutchison M, Bellomo G, Cherepanov A, Stirnal E, Fürtig B, Richter C, Linhard V, Gurewitsch E, Lelli M, Morgner N et al..  2023.  Modulation of Aβ42 aggregation kinetics and pathway by low molecular weight inhibitors. ChemBioChem.
Tröster A, DiPrima M, Jores N, Kudlinzki D, Sreeramulu S, Gande SL, Linhard V, Ludig D, Schug A, Saxena K et al..  2023.  Optimization of the Lead Compound NVP-BHG712 as Colorectal Cancer Inhibitor. Chemistry - A European Journal.
Sudakov A, Knezic B, Hengesbach M, Fürtig B, Stirnal E, Schwalbe H.  2023.  Site-Specific Labeling of RNAs with Modified and 19F-Labelled Nucleotides by Chemo-Enzymatic Synthesis. Chemistry.
2022
Mertinkus KR, Grün JT, Altincekic N, Bains KJ, Ceylan B, Ferner J-P, Frydman L, Fürtig B, Hengesbach M, Hohmann KF et al..  2022.  1H, 13C and 15N chemical shift assignment of the stem-loops 5b+c from the 5'-UTR of SARS-CoV-2. Biomolecular NMR Assignments. 16(1):17-25.
Tsika AC, Gallo A, Fourkiotis NK, Argyriou AI, Sreeramulu S, Löhr F, Rogov VV, Richter C, Linard V, Gande SL et al..  2022.  Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. J. Mol. Biol.. 434(16):167720.
Landgraf T, Völklein AE, Fürtig* B, Schwalbe* H.  2022.  The cotranscriptional folding landscape for two cyclic di-nucleotide-sensing riboswitches with highly homologous aptamer domains acting either as ON- or OFF-switches. Nucl. Acids Res. 50(12):6639-55.
Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel F, Wierenga A, Berge THA, Dennebos R et al..  2022.  Dietary methionine starvation impairs acute myeloid leukemia progression. Blood.
Berg H, Martin WMA, Altincekic N, Alshamleh I, Bains KJ, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C et al..  2022.  Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew. Chem. Intl. Ed.. 61:e202205858.
Kim J, Novakovic M, Jayanthi S, Lupulescu A, Kupce E, Grün T, Mertinkus K, Oxenfarth A, Schwalbe H, Frydman L.  2022.  The Extended Hadamard Transform: Sensitivity-Enhanced NMR Experiments Among Labile and Non-Labile 1Hs of SARS-CoV-2-derived RNAs. ChemPhysChem.
Leisegang MS, Bains KJ, Seredinski S, Oo LA, Krause NM, Kuo C-C, Günther S, Cetin NS, Warwick T, Cao C et al..  2022.  HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nat. Commun. 13( 6563)
Knezic B, Keyhani-Goldau S, Schwalbe H.  2022.  Mapping the conformational landscape of the neutral network of RNA sequences that connect two functional distinctly different ribozymes. ChemBioChem. 23(7):e202200022.
Heering J, Jores N, Kilu W, Schallmayer E, Peelen E, Muehler A, Kohlhof H, Vitt D, Linhard V, Gande SL et al..  2022.  Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators . ACS CHem. Biol..
Niesteruk A, Sreeramulu S, Jonker HRA, Richter C, Schwalbe H.  2022.  Oxidation of the Mycobacterium tuberculosis key virulence factor protein tyrosine phosphatase A (MptpA) reduces its phosphatase activity.. Febs Lett..
Schweizer-Stenner* R, Milorey B, Schwalbe* H.  2022.  Randomizing of oligopeptide conformations by nearest neighbor interactions between amino acids. Biomolecules. 12:684.
Blümler A, Schwalbe* H, Heckel* A.  2022.  Solid-Phase-Supported Chemoenzymatic Synthesis of a Light-Activatable tRNA Derivative.. Angew. Chem. Intl. Ed.. 61:e202111613.
Broft P, Rosenkranz R, Schleiff E, Hengesbach* M, Schwalbe* H.  2022.  Structural analysis of temperature-dependent alternative splicing of HsfA2 pre-mRNA from tomato plants. RNA Biology. 19:266-278.
Schamber T, Binas O, Schlundt A, Wacker A, Schwalbe H.  2022.  Structure and Dynamics of the Guanidine-II Riboswitch from Escherichia coli by NMR Spectroscopy and Small-angle X-ray Scattering (SAXS). ChemBioChem. 23:e20210056410.
Warwick T, Serendinski S, Krause NM, Bains KJ, LAthaus L, Oo JA, Bonetti A, Dueck A, Engelhardt S, Schwalbe H et al..  2022.  A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions . Brief Bioinform. bbac445
2021
Gallo A, Tsika AC, Fourkiotis NK, Cantini F, Banci L, Sreeramulu S, Schwalbe H, Spyroulias GA.  2021.  1H, 13C and 15N chemical shift assignments of the SUD domains of SARS-CoV-2 non-structural protein 3c: "the N-terminal domain-SUD-N".. Biomolecular NMR assignments. 15:85-89. Abstract
Vögele J, Ferner J-P, Altincekic N, Bains KJ, Ceylan B, Fürtig B, Grün JT, Hengesbach M, Hohmann KF, Hymon D et al..  2021.  1H, 13C, 15N and 31P chemical shift assignment for stem-loop 4 from the 5'-UTR of SARS-CoV-2. Biomolecular NMR assignments. 15:335-340.
Richter C, K. F. Hohmann, S. Toews MADN, Toews S, Mathieu D, Altincekic N, Bains KJ, Binas O, Ceylan B, Duchardt-Ferner E, Ferner J et al..  2021.  1H, 13C, and 15N Assignment of Stem-Loop SL1 from the 5'-UTR of SARS-CoV-2. Biomolecular NMR assignments. 15(2):467-474.
Salvi N, Bessa LM, Guseva S, Camcho-Zarco A, Maurin D, Perez LM, Hengesbach M, Korn SM, Schlundt A, Schwalbe H et al..  2021.  1H, 13C, and 15N backbone chemical shift assignments of SARS-CoV-2 Nsp3a. Biomolecular NMR assignments. 15:173-176.
Wang Y, Kirkpatrick J, zur Lage S, Korn SM, Neißner K, Schwalbe H, Schlundt A, Carlomagno T.  2021.  1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein). Biomolecular NMR assignments. 15:287-295.
Schnieders R, Peters SA, Banijamali E, Riad M, Altincekic N, Bains JK, Ceylan B, Fürtig B, Grün JT, Hengesbach M et al..  2021.  1H, 13C, and 15N chemical shift assignments of the stem-loop 5a from the 5‘-UTR of SARS-CoV-2. Biomolecular NMR assignments.
Kim J, Novakovic M, Jayanthi S, Lupulescu A, Kupce E, Grün JT, Mertinkus K, Oxenfarth A, Richter C, Schnieders R et al..  2021.  3D Heteronuclear Magnetization Transfers for the establishment of secondary structures in SARS-CoV-2-derived RNAs. J. Am. Chem. Soc. 143:4942-4948.
Dudás FE, Puglisi R, Korn SM, Alfano C, Bellone ML, Piaz FD, Kelly G, Monaca E, Schlundt A, Schwalbe H et al..  2021.  Backbone chemical shift spectral assignments of SARS coronavirus-2 non-structural protein nsp9.. Biomolecular NMR assignments. 15:235-241.
Sreeramulu S, Richter C, Berg H, Martin WMA, Ceylan B, Matzel T, Adam J, Altincekic N, Azzaoui K, Bains KJ et al..  2021.  Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew. Chem. Int. Ed. Engl.. 60:19191-19200.
Grün JT, Schwalbe H.  2021.  Folding Dynamics of Polymorphic G-Quadruplex Structures. Biopolymers.
Müller D, Bessi I, Richter C, Schwalbe H.  2021.  The folding landscapes of human telomeric RNA and DNA G-quadruplexes are markedly different.. Angew. Chem. Int. Ed. Engl.. 60(19):10895-10901.
Gutt M, Jordan B, Weidenbach K, Gudzuhn M, Kiessling C, Cassidy L, Helbig A, Tholey A, Pyper DJ, Kubatova N et al..  2021.  High complexity of Glutamine synthetase regulation in Methanosarcina mazei: Small protein 26 interacts and enhances glutamine synthetase activity. FEBS J.. 288:5350-5373.
Wienk H, Banci L, Daenke S, Pereiro E, Schwalbe H, Stuart DI, Weiss MS, Perrakis A.  2021.  iNEXT-Discovery and Instrcut-ERIC: Integrating High-End Services for Translational Research in Structural Biology. J. Vis. Exp..
Mueller D, Saha P, Panda D, Dash J, Schwalbe H.  2021.  Insights from Binding on Quadruplex Selective Carbazole Ligands. Chemistry - A European Journal.
Altincekic N, Korn SM, Qureshi NS, Dujardin M, Ninot-Pedrosa M, Abele R, Saad AMJ, Alfano C, Almeida FCL, de Amorim CG et al..  2021.  Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications. Frontiers in Molecular Biosciences. 8:653148.
Novakovic M, Kupce E, Scherf T, Oxenfarth A, Schnieders R, Grün T, Wirmer-Bartoschek J, Richter C, Schwalbe H, Frydman L.  2021.  Magnetization transfer to enhance NOE cross-peaks among labile protons: Applications to imino-imino sequential walks in SARS-CoV-2-derived RNAs. Anew. Chem. Int. Ed. Engl.. 60:11884-11891.
Grund TM, Radloff M, Wu D, Goojani HG, Witte KF, Jösting W, Buschmann S, Müller H, Elamri I, Welsch S et al..  2021.  Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proc. Nat. Acad. Sci. U.S.A. . 118
Baker F, Polat IH, Abou-Al-Ardat K, Alshamleh I, Thoelken M, Hymon D, Gubas A, Koschade SE, Vischedyk JB, Kaulich M et al..  2021.  Metabolic rewiring is essential for AML cell survival to overcome autophagy inhibition by loss of ATG3. Cancer.
Ahmad UDM, Fish A, Molenaar J, Sreeramulu S, Richter C, Altincekic N, Schwalbe H, H.Wienk, Perrakis A.  2021.  Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery. J. Vis. Exp.. 171:e62449.
Knezic B, Binas O, Völklein A, Schwalbe H.  2021.  NMR spectroscopic investigations of ribozymes. Ribozymes.
Qureshi N, Matzel T, Cetiner E, Schnieders R, Jonker HRA, Schwalbe* H, Fürtig B.  2021.  NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs.. Nucl. Acids Res. 49(13):7753-7764.
Berg H, Martin WM, Niesteruk A, Richter C, Sreeramulu S, Schwalbe H.  2021.  NMR-based fragment screening in a minimum sample but maximum automation mode. J. Vis. Exp.. :e62262.
Bocedi A, Cattani G, Gambardella G, Schulte L, Schwalbe H, Ricci G.  2021.  Oxidative Folding of Proteins: The "Smoking Gun" of Glutathione. Int. Journal of Mol. Science. 22:10148.
Harkness R, Hennecker C, Grün JT, Blümler A, Heckel A, Schwalbe H, Mittermaier A.  2021.  Parallel reaction pathways accelerate folding of a guanine quadruplex.. Nucl. Acids Res. 49:1247-1262.
Pintér G, Hohmann KF, Grün TJ, Wirmer-Bartoschek J, Glaubitz C, Fürtig B, Schwalbe H.  2021.  Real-time NMR spectroscopy in the study of biomolecular kinetics and dynamics. Magn. Reson.. 2:291-320.
Millorey B, Schwalbe H, O’Neill N, Schweitzer-Stenner R.  2021.  Repeating aspartic acid residues prefer turn-like conformations in the unfolded state: implications for early protein folding. J. Phys. Chem. B..
Radloff M, Elamri I, Grund TN, Witte LF, Nakagaki S, Goojani HG, Nasiri H, Miyoshi H, Bald D, Xie H et al..  2021.  Short - chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd I and bd-II oxidases. Sci. Rep..