Publications

Found 331 results

2012
Fürtig B, Buck J, Richter C, Schwalbe H.  2012.  Functional dynamics of RNA ribozymes studied by NMR spectroscopy. Ribozymes: Methods and Protocols. 848:185-199. Abstract
Steinert H, Rinnenthal J, Schwalbe H.  2012.  Individual Basepair Stability of DNA and RNA studied by NMR-detected Solvent Exchange. Biophysical J.. 102(11):2564-74.
Verbaro DJ, Mathieu D, Toal SE, Schwalbe H, Schweitzer-Stenner R.  2012.  Ionized Trilysine: A Model System for Understanding the Non-Random Structure of Poly-L-Lysine and Lysine-Containing Motifs in Proteins. J Phys Chem B. . 116(28):8084-8094.
Saxena K, Dutta A, Klein-Seetharaman J, Schwalbe H.  2012.  Isotope labeling in insect cells. Methods Mol Biol.. 831:37-54..
Dutta A, Saxena K, Schwalbe H, Klein-Seetharaman J.  2012.  Isotope labeling in mammalian cells. Methods Mol Biol.. 831:55-69.
Mathieu D, Rybka K, Graf J, Schwalbe H.  2012.  Mapping conformational dynamics in unfolded polypeptide chains using short model peptides by NMR spectroscopy. Peptide Folding, Misfolding, and Nonfolding. :187-219.
Wacker A, Buck J, Richter C, Schwalbe H, Wöhnert J.  2012.  Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches. RNA Biology. 9(5):672-680.
Silvers R, Sziegat F, Tachibana H, Segawa S-ichi, Whittaker S, Günther U, Gabel F, Huang J-rong, Blackledge M, Wirmer-Bartoschek J et al..  2012.  Modulation of Structure and Dynamics by Disulfide Bond Formation in Unfolded States. J. Am. Chem. Soc.. 134(15):6846-54.
Lieblein AL, Krämer M, Dreuw A, Fürtig B, Schwalbe H.  2012.  The nature of the hydrogen bonds in Cytidine-H+-Cytidine DNA base pairs. Angew. Chem. Int. Ed. . 51:4067-4070.
Schieborr U, Sreeramulu S, Schwalbe H.  2012.  NMR structure determination of Protein-Ligand Complexes. NMR of Biomolecules: Towards Mechanistic Systems Biology. :549-561.
Ziegeler* M, Cevec* M, Richter C, Schwalbe H.  2012.  NMR Studies of HAR1 RNA Secondary Structures Reveal Conformational Dynamics in the Human RNA. ChemBioChem. 13:2100-2112.
Cevec M, Jonker HRA, Nozinovic S, Richter C, Schwalbe H.  2012.  Nucleic Acids. NMR of Biomolecules: Towards Mechanistic Systems Biology. :21-31.
Nielsen G, Schwalbe H.  2012.  Protein NMR Spectroscopy: Hydrogen bonds under pressure. Nature Chemistry. 4(9):693-5.
Silvers R, Saxena K, Kudlinzki D, Schwalbe H.  2012.  Recombinant expression and purification of human TATA binding protein using a chimeric fusion. Protein Expression and Purification. 85:142-147.
Ferner J-P, Ferner ED, Rinnenthal J, Buck J, Wöhnert J, Schwalbe H.  2012.  RNA as a Drug Target. NMR of Biomolecules: Towards Mechanistic Systems Biology. :299-313.
Bessi I, Bazzicalupi C, Richter C, Jonker HRA, Saxena K, Sissi C, Chioccioli M, Bianco S, Bilia AR, Schwalbe H et al..  2012.  Spectroscopic, molecular modeling and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA. ACS Chemical Biology. 7(6):1109-1119.
Lieblein AL, Buck J, Schlepckow K, Fürtig B, Schwalbe H.  2012.  Time-resolved NMR studies of DNA i-motif folding reveal kinetic partitioning. Angew. Chem.Intl. Ed. Engl.. 51:250-253.
Angerer H, Nasiri HR, Niedergesäß V, Kirscher S, Schwalbe H, Brandt U.  2012.  Tracing the tail of ubiquinone in mitochondrial complex I. BBA Bioenergetics. 1817(10):1776-84.
2011
Nozinovic S, Gupta P, Fürtig B, Richter C, Tüllmann S, Ferner-Duchardt E, Holthausen M, Schwalbe H.  2011.  2'OH Group Conformation in RNA derived from NMR spectroscopy and DFT calculations. Angew. Chem. Intl. Ed. Engl.. 50(23):5397-400.
Hagarman A, Mathieu D, Toal S, Measey TJ, Schwalbe H, Schweitzer-Stenner R.  2011.  Amino Acids with Hydrogen Bonding Side Chains have an Intrinsic Tendency to Sample Various Turn Conformations in Aqueous Solution. Chemistry - A European Journal. 17(24):6789-97.
Sziegat F, Wirmer-Bartoschek J, Schwalbe H.  2011.  Characteristics of Human Lysozyme and Its Disease-Related Mutants in their Unfolded States. Angew. Chem. Intl. Ed. Engl.. 50:5514-8.
Schwalbe H.  2011.  Commentary: Double Take on PiWi Protein/piRNA Complex Structure. Structure. 19(2):141-142.
katja Barthelmes, Reynolds A, Peizach E, Jonker HRA, Denunzio N, Allen K, Imperiali B, Schwalbe H.  2011.  Engineering Encodable Lanthanide-Binding Tags (LBTs) into Loop Regions of Proteins. J. Am. Chem. Soc.. 133:808-819. Abstract
Buck J, Wacker A, Warkentin E, Wöhnert J, Wirmer-Bartoschek J, Schwalbe H.  2011.  Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain. Nucleic Acids Res.. 39:9768-9778.
Salvatore DB, Duraffourg N, Favier A, Persson BA, Lund M, Delage M-M, Silvers R, Schwalbe H, Croguennec T, Bouhallab S et al..  2011.  Investigation at residue level of the early steps during the assembly of two proteins into supramolecular objects. Biomacromolecules. 12(6):2200-2210. Abstract
Rinnenthal J, Buck J, Ferner J, Wacker A, Fürtig B, Schwalbe H.  2011.  Mapping the Landscape of RNA Dynamics with NMR spectroscopy. Accounts of Chemical Research. 44(12):1292-301.
Rinnenthal J, Klinkert B, Narberhaus F, Schwalbe H.  2011.  Modulation of the stability of the Salmonella fourU-type RNA thermometer. Nucleic Acids Res.. 39:8258-8270.
Nielsen G, Schwalbe H.  2011.  NMR spectroscopic investigations of the activated p38alpha mitogen-activated kinase. ChemBioChem. 12(17):2599-2607.
Jonker HRA, Baumann S, Wolf A, Schoof S, Hiller F, Schulte KW, Kirschner KN, Schwalbe H, Arndt H-D.  2011.  NMR structures of Thiostrepton derivatives report target shape recognition. Angew. Chem. Intl. Ed. Engl.. 50:3308-3312. Abstract
Englert NE, Richter C, Wiesner J, Hintz M, Jomaa H, Schwalbe H.  2011.  NMR studies of DOXP reductoisomerase and its inhibitor complexes. ChemBioChem. 12(3):468-76. Abstract
Silvers R, Schlepckow K, Wirmer-Bartoschek J, Schwalbe H.  2011.  NMR-spectroscopic Investigation of Disulfide Dynamics in Unfolded States of Proteins. Folding of disulfide proteins.
Fürtig B, Buck J, Rinnenthal J, Wacker A, Schwalbe H.  2011.  NMR-Spektroskopie zum Verständnis von RNA-basierter Regulation. Biospektrum. 17:174-177.
Schlepckow K, Fürtig B, Schwalbe H.  2011.  Nonequilibrium NMR methods for monitoring protein and RNA folding. Zeitschrift für Physikalische Chemie. 225:611-636.
Reckel S, Gottstein D, Stehle J, Löhr F, Verhoefen M-K, Takeda M, Silvers R, Kainosho M, Glaubitz C, Wachtveitl J et al..  2011.  Solution NMR Structure of Proteorhodopsin. Angew. Chem. Intl. Ed. Engl.. 50:11942-11946.
Wacker A, Buck J, Mathieu D, Richter C, Wöhnert J, Schwalbe H.  2011.  Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR spectroscopy. Nucleic Acids Res. 39(15):6802-12. Abstract
Kortmann J, Sczodrok S, Rinnenthal J, Schwalbe H, Narberhaus F.  2011.  Translation on demand by a simple RNA-based thermosensor. Nucleic Acids Res.. 39:2855-2868. Abstract
2010
Schwalbe H, Rinnenthal J.  2010.  Thermodynamics: the world is flat. Nat Chem Biol. 6:312–313.
Rinnenthal J, Klinkert B, Narberhaus F, Schwalbe H.  2010.  Direct observation of the temperature-induced melting process of the Salmonella fourU RNA thermometer at base-pair resolution.. Nucleic Acids Res. 38:3834–3847.. Abstract
Buck J, Noeske J, Wöhnert J, Schwalbe H.  2010.  Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain.. Nucleic Acids Res. 38:4143-4153. Abstract
Doller A, Schlepckow K, Schwalbe H, Pfeilschifter J, Eberhardt W.  2010.  Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR.. Mol Cell Biol. 30:1397–1410. Abstract
Nozinovic S, Fürtig B, Jonker HRA, Richter C, Schwalbe H.  2010.  High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA.. Nucleic Acids Res. 38:683–694. Abstract
Hähnke MJ, Richter C, Heinicke F, Schwalbe H.  2010.  The HN(COCA)HAHB NMR experiment for the stereospecific assignment of Hbeta-protons in non-native states of proteins.. J Am Chem Soc. 132:918–919. Abstract
Hagarman A, Measey TJ, Mathieu D, Schwalbe H, Schweitzer-Stenner R.  2010.  Intrinsic propensities of amino acid residues in GxG peptides inferred from amide I' band profiles and NMR scalar coupling constants.. J Am Chem Soc. 132:540–551. Abstract
Gerum C, Schlepckow K, Schwalbe H.  2010.  The Unfolded State of the Murine Prion Protein and Properties of single-point mutants related to human prion diseases. J Mol Biol. 401:7-12. Abstract
Richter C, Kovacs H, Buck J, Wacker A, Fürtig B, Bermel W, Schwalbe H.  2010.  13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides. J Biomol NMR. 47(4):259-69. Abstract
Cao S, Fürtig B, Schwalbe H, Chen S-J.  2010.  Folding Kinetics for the Conformational Switch between Alternative RNA Structures. The Journal of Physical Chemistry B. 114(42):13609-13615. Abstract
Cherepanov A, Glaubitz C, Schwalbe H.  2010.  High-Resolution Studies of Uniformly 13C,15N-Labeled RNA by Solid-State NMR Spectroscopy. Angew. Chem. Intl. Ed. Engl.. 49:4747-4750.
Silvers R, Buhr F, Schwalbe H.  2010.  Highlight: The molecular mechanism of spider silk formation. Angew. Chem. Int. Ed. Engl.. 49:5410-5412. Abstract
Saxena K, Schieborr U, Anderka O, Duchardt-Ferner E, Elshorst B, Gande SL, Janzon J, Kudlinzki D, Sreeramulu S, Dreyer MK et al..  2010.  Influence of heparin mimetics on the assembly of the FGF - FGFR4 signaling complex. J. Biol. Chem.. 285:26628-26640. Abstract
Dastvan R, Bode B, Karuppiah MPR, Marko A, Lyubenova S, Schwalbe H, Prisner T.  2010.  Optimization of Transversal Relaxation of Nitroxides for PELDOR Spectroscopy in Phospholipid Membranes. The Journal of Physical Chemistry B. 114(42):13507-16. Abstract