Found 37 results
Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTNI). Biosensors. 13:455.
.
2023.
COVID19-NMR consortium: A public report on the impact of this new global collaboration. Angew. Chem. Intl. Ed.. :e202217171.
.
2023.
Crystal structure of the CoV-Y domain of SARS-CoV-2 nonstructural protein 3.. Sci Rep.. 13(1):2890.
.
2023.
Optimization of the Lead Compound NVP-BHG712 as Colorectal Cancer Inhibitor. Chemistry - A European Journal.
.
2023.
Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. J. Mol. Biol.. 434(16):167720.
.
2022.
Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew. Chem. Intl. Ed.. 61:e202205858.
.
2022.
.
2022.
Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew. Chem. Int. Ed. Engl.. 60:19191-19200.
.
2021.
Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications. Frontiers in Molecular Biosciences. 8:653148.
.
2021.
Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery. J. Vis. Exp.. 171:e62449.
.
2021.
NMR-based fragment screening in a minimum sample but maximum automation mode. J. Vis. Exp.. :e62262.
.
2021.
The transcriptional repressor orphan nuclear receptor TLX is responsive to xanthines.. ACS Pharmacol. Transl. Sci.. 4:1794-1807.
.
2021.
1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10. Biomolecular NMR assignments.
.
2020.
1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP‑ribose bound forms of the macrodomain of SARS‑CoV‑2 non‑structural protein 3b. Biomolecular NMR assignments. 14(2):339-346.
.
2020.
.
2020.
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nat Commun. . 11(1):5569.
.
2020.
Gemeinschaftlich in Krisenzeiten: NMR-Strukturbiologie gegen COVID-19. BIOspektrum. 26:440-441.
.
2020.
NMR Quality Control of Fragment Libraries for Screening. J. Biomol. NMR. 74:555-563.
.
2020.
.
2020.
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy. Nucl. Acids Res. 48(22):12415-12435.
.
2020.
Strukturbiologie von SARS-CoV-2 mit NMR-Spektroskopie. Nachrichten aus Chemie und Technik. 68:55-58.
.
2020.
Molecular tuning of farnesoid X receptor partial agonism. Nature Comm.. 10(1):2915.
.
2019.
Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation. Nucl. Acids Res.. 46:10917-10929.
.
2018.
.
2018.
.
2018.
NVP-BHG712: Effects of regioisomers on the affinity and selectivity towards the EPHrin family. ChemMedChem. 13:2358-2464.
.
2018.
On the implication of water on fragment-to-ligand growth in kinase binding thermodynamics. ChemMedChem. 13:1988-1996.
.
2018.
.
2018.
Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor. Chemistry - A European Journal. 24:7861-7865.
.
2018.
.
2018.
Chemoproteomics-aided medicinal chemistry for the discovery of EPHA2 inhibitors. ChemMedChem. 12(12):999-1011.
.
2017.
.
2016.
High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.. Acta Crystallogr F Struct Biol Commun.. 71:1088-93.
.
2015.
Optimized Plk1 PBD inhibitors based on Poloxin induce mitotic arrest and apoptosis in tumor cells. ACS Chemical Biology. 10(11):2570-9.
.
2015.
.
2013.
MOTOR: Model assisted Software for NMR Structure Determination. Proteins. 81:2007-2022.
.
2013.