Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding
| Title | Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Wienen-Schmidt B, Jonker HRA, Wulsdorf T, Gerber H-D, Saxena K, Kudlinzki D, Sreeramulu S, Parigi G, Luchinat C, Heine A, Schwalbe* H, Klebe* G |
| Journal | J. Med. Chem. |
| Volume | 61 |
| Pagination | 5922-5933 |
| URL | http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/51313 |