Publications

Found 25 results

2023
Vögele J, Hymon D, Martins J, Ferner J, Jonker HRA, Hargrove AE, Wacker A, Schwalbe H, Wöhnert J, Duchardt-Ferner E.  2023.  High-resolution structure of stem-loop 4 from the 5'-UTR of SARS-CoV-2 solved by solution state NMR. Nucl. Acids Res.. 51:11318-11331.
Oxenfarth A, Kümmerer F, Battaro S, Schnieders R, Pinter G, Jonker HRA, Fürtig B, Richter C, Blackledge M, Lindorff-Larsen K et al..  2023.  Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a thermodynamically stable CUUG RNA tetraloop. JACS. 145:16557-16572.
2022
Leisegang MS, Bains KJ, Seredinski S, Oo LA, Krause NM, Kuo C-C, Günther S, Cetin NS, Warwick T, Cao C et al..  2022.  HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nat. Commun. 13( 6563)
Niesteruk A, Sreeramulu S, Jonker HRA, Richter C, Schwalbe H.  2022.  Oxidation of the Mycobacterium tuberculosis key virulence factor protein tyrosine phosphatase A (MptpA) reduces its phosphatase activity.. Febs Lett..
2021
Richter C, K. F. Hohmann, S. Toews MADN, Toews S, Mathieu D, Altincekic N, Bains KJ, Binas O, Ceylan B, Duchardt-Ferner E, Ferner J et al..  2021.  1H, 13C, and 15N Assignment of Stem-Loop SL1 from the 5'-UTR of SARS-CoV-2. Biomolecular NMR assignments. 15(2):467-474.
Qureshi N, Matzel T, Cetiner E, Schnieders R, Jonker HRA, Schwalbe* H, Fürtig B.  2021.  NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs.. Nucl. Acids Res. 49(13):7753-7764.
2020
Jonker HRA, Saxena K, Shcherbakova A, Tiemann B, Bakker H, Schwalbe H.  2020.  NMR characterization of the C-mannose conformation in a trombospondin repeat using a selective labeling approach. Angew. Chem. Int. Ed. Engl..
2019
Cetiner EC, Jonker HRA, Helmling C, Gophane DB, Grünewald C, Sigurdsson ST, Schwalbe H.  2019.  Paramagnetic-Iterative Relaxation Matrix Approach – Extracting PRE-Restraints from NOESY Spectra for 3D Structure Elucidation of Biomolecules. J. Biomol. NMR. 73(12):699-712.
Kubatova N, Pyper DJ, Jonker HRA, Saxena K, Remmel L, Richter C, Brantl S, Evguenieva-Hackenberg E, Hess W, Klug G et al..  2019.  Rapid biophysical characterization and NMR structural analysis ofsmall proteins from bacteria and archaea. ChemBioChem.
Kubatova N, Jonker HRA, Saxena K, Richter C, Vogel V, Schreiber S, Marchfelder A, Schwalbe H.  2019.  Solution structure and dynamics of the small protein HVO_2922 from Haloferax volcanii. ChemBioChem. 21(1-2):149-156.
2018
Niesteruk A, Jonker HRA, Richter C, Linhardt V, Sreeramulu S, Schwalbe H.  2018.  The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture. J. Biol. Chem.. 293 :11823-11836.
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J et al..  2018.  The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.. Nat. Chem. Biol.. 14:284-290.
Wienen-Schmidt B, Wulsdorf T, Jonker HRA, Saxena K, Kudlinzki D, Linhard V, Sreeramulu S, Heine A, Schwalbe H, Klebe G.  2018.  On the implication of water on fragment-to-ligand growth in kinase binding thermodynamics. ChemMedChem. 13:1988-1996.
Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker HRA, Stelzl L, Hummer G, Schwalbe* H et al..  2018.  Optimal destabilization of DNA double strands by single-nucleobase caging. Chemistry. 24:17568-17576.
Wienen-Schmidt B, Jonker HRA, Wulsdorf T, Gerber H-D, Saxena K, Kudlinzki D, Sreeramulu S, Parigi G, Luchinat C, Heine A et al..  2018.  Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding. J. Med. Chem.. 61:5922-5933.
Kappert F, Sreeramulu S, Jonker HRA, Richter C, Rogov VV, Proschak E, Hargittay B, Saxena K, Schwalbe H.  2018.  Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor. Chemistry - A European Journal. 24:7861-7865.
Niesteruk A, Hutchison M, Sreeramulu S, Jonker HRA, Richter C, Abele R, Bock C, Schwalbe H.  2018.  Structural characterization of the Intrinsically Disordered Domain (IDD) of Mycobacterium tuberculosis Protein Tyrosine Kinase A (PtkA). FEBS Lett.. 592(7):1233-1245.
Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O et al..  2018.  Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat. Commun..
2017
Barthelmes D, Barthelmes K, Schnorr K, Jonker HRA, Bodmer B, Allen KN, Imperiali B, Schwalbe H.  2017.  Conformational dynamics and alignment properties of lopp Lanthanide-Binding-Tags (LBTs) studied in Interleukin-1beta. J. Biomol. NMR. 68(3):187-194.
Schnorr K, Gophane DB, Helmling C, Cetiner E, Pasemann K, Fürtig B, Wacker A, Qureshi NS, Gränz M, Barthelmes D et al..  2017.  Impact of spin label rigidity on extent and accuracy of distance information from PRE data. J. Biomol. NMR. 68(1):53-63.
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J et al..  2017.  The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol..
Wirmer-Bartoschek J, Bendel LE, Jonker HRA, Grün JT, Papi F, Bazzicalupi C, Messori L, Gratteri* P, Schwalbe* H.  2017.  The NMR solution structure of a ligand/hybrid-2-G-quadruplex complex reveals structural rearrangements that facilitate ligand binding. Angew. Chem. Intl. Ed.. 56:7102-7106.
2016
Thevarpadam' J, Bessi' I, Binas' O, Schmidt DG, Slavov C, Jonker HRA, Wachtveitl J, Schwalbe* H, Heckel* A.  2016.  Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif. Angew. Chem. Int. Ed.. 55(8):2738-42.
Heering J, Jonker HRA, Löhr F, Schwalbe H, Dötsch V.  2016.  Structural investigations oft he p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci.. 25(2):410-22.
2013
Nielsen G, Jonker HRA, Vajpaj N, Grzesiek S, Schwalbe H.  2013.  Kinase in motion: insights into the dynamic nature of p38alpha by high pressure NMR spectroscopic studies.. ChemBioChem. 14:1799-1806.