Found 16 results
Targeting main protease (Mpro, nsp5) by growth of fragment scaffolds exploiting structure-based methodologies. ACS Chem. Biol. . 19:563-574.
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2024.
Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTNI). Biosensors. 13:455.
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2023.
Optimization of the Lead Compound NVP-BHG712 as Colorectal Cancer Inhibitor. Chemistry - A European Journal.
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2023.
Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity. J. Mol. Biol.. 434(16):167720.
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2022.
Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew. Chem. Intl. Ed.. 61:e202205858.
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2022.
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2022.
Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications. Frontiers in Molecular Biosciences. 8:653148.
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2021.
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2021.
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2020.
1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP‑ribose bound forms of the macrodomain of SARS‑CoV‑2 non‑structural protein 3b. Biomolecular NMR assignments. 14(2):339-346.
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2020.
Light dynamics of retinal disease-relevant G90D bovine rhodopsin mutant. Angew. Chem. Int. Ed. Engl.. 59:15656–15664.
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2020.
Molecular tuning of farnesoid X receptor partial agonism. Nature Comm.. 10(1):2915.
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2019.
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2018.
NVP-BHG712: Effects of regioisomers on the affinity and selectivity towards the EPHrin family. ChemMedChem. 13:2358-2464.
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2018.
Chemoproteomics-aided medicinal chemistry for the discovery of EPHA2 inhibitors. ChemMedChem. 12(12):999-1011.
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2017.
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2016.