Publications

Found 450 results

2020
Gallo A, Tsika AC, Fourkiotis NK, Cantini F, Banci L, Sreeramulu S, Schwalbe H, Spyroulias GA.  2020.  1H,13C, and 15N chemical shift assignments of the SUD domains of SARS-CoV-2 non-structural protein 3c: "The SUD-M and SUD-C domains". Biomolecular NMR assignments.
Saidi I, Nimbarte V, Schwalbe H, Waffo-Téguo P, Harrath HA, Mansour L, Alwasel S, Jannet HB.  2020.  Anti-tyrosinase, anti-cholinesterase and cytotoxic activities of extracts and phytochemicals from the Tunisian Citharexylum spinosum L.: Molecular docking and SAR analysis. Bioorg. Chem.. 102:104093.
Zahn S, Kubatova N, Pyper DJ, L. Cassidy, Saxena K, Tholey A, Schwalbe H, Soppa J.  2020.  Biological functions, genetic and biochemical characterization, and NMR structure determination of the small zinc finger protein HVO_2753 from Haloferax volcanii. Febs J..
Grün JT, Hennecker C, Klötzner D-P, Harkness R, Bessi I, Heckel A, Mittermaier* A, Schwalbe* H.  2020.  Conformational Dynamics of Strand Register Shifts in DNA G-quadruplexes. J. Am. Chem. Soc.. 142(1):264-273.
Binas O, Schamber T, Schwalbe H.  2020.  The conformational landscape of transcription intermediates involved in the regulation of the ZMP-sensing riboswitch from Thermosinus carboxydivorans. Nucl. Acids Res. 48(12):6970-9.
Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hordinau VV, Meier-Credo J, Saxena K, Buhr F, Langer JD et al..  2020.  Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nat Commun. . 11(1):5569.
Chiapparino A, Grbavac A, Jonker HR, Hackmann Y, Mortensen S, Zatorska E, Schott A, Stier G, Saxena K, Wild K et al..  2020.  Functional implications of MIR domains in protein O-mannosylation. eLife. 9:e61189.
Schlundt A, Martin WMA, Knezic B, Hengesbach M, Fürtig B, Weigand JE, Wöhnert J, Ferner J, Saxena K, Wacker A et al..  2020.  Gemeinschaftlich in Krisenzeiten: NMR-Strukturbiologie gegen COVID-19. BIOspektrum. 26:440-441.
Müller D, Trucks S, Schwalbe H, Hengesbach M.  2020.  Genetic code expansion facilitates position-selective modification of nucleic acids and proteins. ChemPlusChem. 85:1233-1243.
Saha P, Panda D, Müller D, Maity A, Schwalbe H, Dash J.  2020.  In situ formation of transcriptional modulators by non-canonical DNA i-motifs. Chemical Sci. 11(8):2058-2067.
Broft P, Dzatko S, Krafcikova M, Hansel-Hertsch R, Wacker A, Doetsch V, Trantirek* L, Schwalbe* H.  2020.  In-cell NMR of functional riboswitch aptamers in eukaryotic cells. Angew. Chem. Int. Ed. Engl..
Kubatova N, Mao J, Eckert CE, Saxena K, Gande SL, Wachtveitl* J, Glaubitz* C, Schwalbe* H.  2020.  Light dynamics of retinal disease-relevant G90D bovine rhodopsin mutant. Angew. Chem. Int. Ed. Engl.. 59:15656–15664.
Jonker HRA, Saxena K, Shcherbakova A, Tiemann B, Bakker H, Schwalbe H.  2020.  NMR characterization of the C-mannose conformation in a trombospondin repeat using a selective labeling approach. Angew. Chem. Int. Ed. Engl..
Sreeramulu S, Richter C, Kühn T, Azzaoui K, Blommers MJJ, Conte DR, Fragai M, Trieloff N, Schmieder P, Nazaré M et al..  2020.  NMR Quality Control of Fragment Libraries for Screening. J. Biomol. NMR. 74:555-563.
Schnieders R, Knezic B, Zetzsche H, Sudakov A, Matzel T, Richter C, Hengesbach M, Schwalbe H, Fürtig B.  2020.  NMR spectroscopy of large functional RNAs - from sample preparation to low-gamma-detection. Current protocols in Nucl. Acids. 82(e116)
Wenger KJ, Richter C, Burger MC, Urbans H, Kaulfuss S, Jarter PN, Sreeramulu S, Schwalbe H, Steinbach JP, Hattingen E et al..  2020.  Non-invasive measurement of drug a 2-HG signals using 19F and 1H MR spectroscopy in brain tumors treated with the mutant IDH1 inhibitor BAY1436032.. Cancers. 12:E3175.
Neuber C, Tröster A, Löser R, Belter B, Schwalbe H, Pietzsch J.  2020.  The Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitor NVP-BHG712: Effects of Regioisomers on Tumor Growth, Perfusion, and Hypoxia in EphB4-Positive A375 Melanoma Xenografts.. Molecules. 25(21):E5115.
Parra-Rojas C, Fürtig B, Schwalbe H, Esteban H-V.  2020.  Quantitative modeling of the function of kinetically driven transcriptional riboswitches. J. Theor. Biol.. 505:110406.
Aslamleh I, Krause N, Richter C, Kurrle N, Serve H, Günther UL, Schwalbe H.  2020.  Real-time NMR for studying metabolism. Angew. Chem. Int. Ed. Engl.. 59(6):2304-2308.
Pinter G, Schwalbe H.  2020.  Refolding of cold denatured barstar induced by radio frequency heating – new method to study protein folding by real-time NMR spectroscopy. Angew. Chem. Int. Ed. Engl..
Fürtig B, Oberhauser EM, Zetzsche H, Klötzner DP, Heckel A, Schwalbe H.  2020.  Refolding through a linear transition state enables fast temperature adaptation of a translational riboswitch. Biochemistry. 59(10):1081-1086.
Wacker A, Weigand JE, Akabayov S-R, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martínez J, Cetiner E, Ceylan B et al..  2020.  Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy. Nucl. Acids Res. 48(22):12415-12435.
Novakovic M, Kupče Ē, Oxenfarth A, Battistel MD, Freedberg DI, Schwalbe H, Frydman L.  2020.  Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids. Nat. Comm. 11 (1):5317.
Altincekic N, Löhr M, Meier-Credo J, Langer J, Hengesbach M, Richter C, Schwalbe H.  2020.  Site-specific detection of arginine methylation in highly repetitive protein motifs of low sequence complexity by NMR. J. Am. Chem. Soc. 142(16):7647-7654.
Heiliger J, Matzel T, Cetiner EC, Schwalbe* H, Kuenze* G, Corzilius B.  2020.  Site-specific dynamic nuclear polarization in a Gd(III)-labeled protein. Chem. Phys. Phys. Chem..
Zhou S, Ruan M, Li Y, Yang J, Bai S, Richter C, Schwalbe H, Xie C, Shen B, Wang J.  2020.  Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide . Cell Res.
Binas O, Tants JN, Peters S, Janowski R, Davydova E, Braun J, Niessing D, Schwalbe H, Weigand J, Schlundt A.  2020.  Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucl. Acids Res.. 48(13):7385-7403.
Lieblein T, Zangl R, Martin J, Hoffmann J, Hutchinson M, Stark T, Stirnal E, Schrader T, Schwalbe H, Morgner N.  2020.  Structural Rearrangement of Amyloid-beta upon Inhibitor Binding Suppresses Formation of Alzheimer's Disease Related Oligomers. eLife. 9:e59306.
Binas O, Bessi I, Schwalbe H.  2020.  Structure validation for G-rich RNAs in non-coding regions of the human genome. ChemBioChem. 21(11):1656-1663.
Weigand JE, Ferner J, Fürtig B, Hacker C, Hähnke M, Hengesbach M, Richter C, Saxena K, Schlundt A, Sreeramulu S et al..  2020.  Strukturbiologie von SARS-CoV-2 mit NMR-Spektroskopie. Nachrichten aus Chemie und Technik. 68:55-58.
Elamri I, Radloff M, Hohmann KF, Nimbarte VD, Nasiri HR, Bolte M, Safarian S, Michel H, Schwalbe H.  2020.  Synthesis and biological screening of new lawson derivatives as selective substrate-based inhibitors of cytochrome bo3 ubiquinol oxidase from Escherichia coli.. ChemMedChem. 15:1262-1271.
2019
Shi YN, Pusch S, Shi YM, Richter C, Macia-Vicente JG, Schwalbe H, Kaiser M, Opatz T, Bode HB.  2019.  (±) Alternarlactones A and B, two antiparasitic alternariol-like dimers from the fungus Alternaria alternate P1210 isolated from the halophyte Salicornia sp.. J. Org. Chem.. 84(17):11203-11209.
Rehbein* P, Berz J, Kreisel P, Schwalbe H.  2019.  Codon Wizard – An intuitive software tool for customizable codon optimization in protein expression efforts with graphical user interface.. Protein Expr Purif.. 19:S1046-5928.
Bains JK, Blechar J, de Jesus V, Meiser N, Fürtig B, Schwalbe H, Hengesbach M.  2019.  Combined smFRET and NMR analysis of riboswitch structural dynamics. Methods. S1046-2023(18):30303-7.
Rehbein P, Raguz N, Schwalbe H.  2019.  Evaluating mechanical properties of silica-coated alginate beads for immobilized biocatalysis. Biochemical Engineering Journal . 141:225-231.
Saha P, Kumar YP, Das T, Müller D, Bessi I, Schwalbe H, Das J.  2019.  A G-quadruplex Specific Cell-Permeable Guanosine-Anthracene Conjugate Inhibits Telomere Elongation and Induces Apoptosis by Repressing c-MYC Gene. Bioconjugate Chem.. 30(12):3038-3045.
DiPrima M, Wang D, Tröster A, Maric D, Terrades-Garcia N, Ha T, Kwak H, Sanchez-Martin D, Kudlinzki D, Schwalbe H et al..  2019.  Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma.. Mol. Oncol.. 13(11):2441-2459.
Kreitz J, Schönfeld C, Seibert M, Stolp V, Alshamleh I, Oellerich T, Steffen B, Schwalbe H, Schnütgen F, Kurrle N et al..  2019.  Metabolic Plasticity of Acute Myeloid Leukemia. Cells. 8(8):E805.
Reese M, George C, Yang C, Jawla S, Grün TJ, Schwalbe H, Redfield C, Temkin RJ, Griffin RG.  2019.  Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz. J. Magn. Reson.. 307:106573.
Merk* D, Sreeramulu S, Kudlinzki D, Saxena K, Linhardt V, Gande SL, Hiller F, Lamers C, Nilsson E, Aagard A et al..  2019.  Molecular tuning of farnesoid X receptor partial agonism. Nature Comm.. 10(1):2915.
Schnieders R, Keyhani S, Schwalbe* H, Fürtig* B.  2019.  More than Proton Detection – New Avenues for NMR of RNA. Chemistry. 26(1):102-111.
Schnieders R, Wolter AC, Richter C, Wöhnert J, Schwalbe* H, Fürtig* B.  2019.  Novel 13C-detected NMR experiments for precise detection of RNA structure. Angew. Chem. Int. Ed.. 58(27):9140-9144.
Cetiner EC, Jonker HRA, Helmling C, Gophane DB, Grünewald C, Sigurdsson ST, Schwalbe H.  2019.  Paramagnetic-Iterative Relaxation Matrix Approach – Extracting PRE-Restraints from NOESY Spectra for 3D Structure Elucidation of Biomolecules. J. Biomol. NMR. 73(12):699-712.
Kubatova N, Pyper DJ, Jonker HRA, Saxena K, Remmel L, Richter C, Brantl S, Evguenieva-Hackenberg E, Hess W, Klug G et al..  2019.  Rapid biophysical characterization and NMR structural analysis ofsmall proteins from bacteria and archaea. ChemBioChem.
Kubatova N, Jonker HRA, Saxena K, Richter C, Vogel V, Schreiber S, Marchfelder A, Schwalbe H.  2019.  Solution structure and dynamics of the small protein HVO_2922 from Haloferax volcanii. ChemBioChem. 21(1-2):149-156.
2018
Dutta D, Debnanth M, Müller D, Paul R, Das T, Bessi I, Schwalbe H, Dash J.  2018.  Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex. Nucl. Acids Res.. 46:5355-5365.
Keyhani S, Goldau T, Blümler A, Heckel* A, Schwalbe* H.  2018.  Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy. Angew. Chem. Int. Ed.. 57:12017-12021.
Qureshi NS, Sreeramulu S, Bains JK, Schwalbe* H, Fürtig* B.  2018.  Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation. Nucl. Acids Res.. 46:10917-10929.
Niesteruk A, Jonker HRA, Richter C, Linhardt V, Sreeramulu S, Schwalbe H.  2018.  The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture. J. Biol. Chem.. 293 :11823-11836.
Coutinho ID, Henning LMM, Döpp SA, Mepomuceno A, Morales LAC, Marcolino-Gomes J, Richter C, Schwalbe H, Colnago LA.  2018.  Flooded soybean metabolomic analysis reveals important primary and secondary metabolites involved in the hypoxia stress response and tolerance. Environmental and Experimental Biology. 153:176-187.