Publications

Found 364 results

2017
Bessi I, Wirmer-Bartoschek J, Dash J, Schwalbe H.  2017.  Targeting G-quadruplex with small molecules: an NMR view. Modern Magnetic Resonance: 2nd edition.
Pinter G, Schwalbe H.  2017.  Unprecedented carbon signal enhancement in liquid-state NMR spectroscopy. Angew, Chem. Int. Ed. . 56(29):8332-8334.
2016
Sochor F, Silvers R, Müller D, Richter C, Fürtig B, Schwalbe H.  2016.  19F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy.. J Biomol NMR. 64(1):63-74.
Grothe J, Krysciak D, Petersen K, Güllert S, Förstner KU, Krishnan HB, Schwalbe H, Kubatova N, Streit W.  2016.  The Absence of the N-acyl-homoserine-lactone Autoinducer Synthase Genes traI and ngrI Increases the Copy Number of the Symbiotic Plasmid in Sinorhizobium fredii NGR234. Front. Microbiol.. 7:1858.
Stellos K, Gatsiou A, Stamatelopoulos K, Matic LP, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F et al..  2016.  Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.. Nat. Medicine. 22:1140-1150.
Nasiri AH, Saxena K, Bats JW, Nasiri HR, Schwalbe H.  2016.  Biophysical investigation and conformational analysis of p38α kinase inhibitor doramapimod and its analogues. MedChemCom. 7:1421-1428.
Heinzlmeir# S, Kudlinzki# D, Sreeramulu S, Klaeger S, Gande SL, Linhardt V, Wilhelm M, Qiao H, Helm D, Ruprecht B et al..  2016.  Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs.. ACS Chem. Biol..
Hahn J, Thalmann S, Migur A, von Boeselager FR, Kubatova N, Kubareva E, Schwalbe H, Evguenieva-Hackenberg E.  2016.  Conserved small mRNA with an unique, extended Shine-Dalgarno sequence. RNA Biol..
Fürtig B, Schnieders R, Richter C, Zetzsche H, Keyhani S, Helmling C, Kovacs H, Schwalbe H.  2016.  Direct 13C-detected NMR Experiments for Mapping and Characterization of Hydrogen Bonds in RNA. J. Biomol. NMR. 64(3):207-21.
Gande SL, Saxena K, Sreeramulu S, Linhard V, Kudlinzki D, Heinzlmeir S, Reichert AJ, Skerra A, Küster B, Schwalbe H.  2016.  Expression and purification of EPHA2 tyrosine kinase domain for crystallographic and NMR studies.. ChemBioChem. 17(23):2257-2263.
Kumar PY, Saha P, Saha D, Bessi I, Schwalbe H, Chowdhurz S, Dash J.  2016.  Fluorescent Dansyl-guanosine Conjugates That Bind c-MYC Promoter G-quadruplex and Down-regulate c-MYC Expression. Chembiochem. 17(5):388-93.
Kaushik M, Bahrenberg T, Can TV, Caporini MA, Silvers R, Heiliger J, Smith AA, Schwalbe H, Griffin RG, Corzilius B.  2016.  Gd(iii) and Mn(ii) complexes for dynamic nuclear polarization: small molecular chelate polarizing agents and applications with site-directed spin labeling of proteins.. Phys Chem Chem Phys. 18:27205-27218.
Daube D, Aladin V, Heiliger J, Wittmann J, Barthelmes D, Schwalbe H, Corzilius B.  2016.  Heteronuclear cross-relaxation under solid-state dynamic nuclear polarization. J. Am. Chem. Soc.. 138(51):16572-16575.
Thevarpadam' J, Bessi' I, Binas' O, Schmidt DG, Slavov C, Jonker HRA, Wachtveitl J, Schwalbe* H, Heckel* A.  2016.  Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif. Angew. Chem. Int. Ed.. 55(8):2738-42.
Henker J, Wirmer-Bartoschek J, Bendel LE, Xiang YG, Fu C, Harms K, Schwalbe H, Meggers E.  2016.  Progress in the synthesis and bioactivity of hexacoordinate silicon (IV) complexes. European Journal of Inorganic Chemistry. 32(5161-5170)
Zhu W, Silvers R, Schwalbe H, Keiderling T.  2016.  Reduced and mutant lysozyme refolding with lipid vesicles. Model study of impact of disulfides on equilibria and dynamics.. Biochim Biophys Acta. 1864(9):1083-92.
Debnath M, Ghosh S, Panda D, Bessi I, Schwalbe H, Bhattacharyya K, Dash J.  2016.  Small Molecule Regulated Dynamic Structural changes of Human G-quadruplexes. Chemical Science. 7:3279-3285.
Heering J, Jonker HRA, Löhr F, Schwalbe H, Dötsch V.  2016.  Structural investigations oft he p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci.. 25(2):410-22.
Buhr F, Jha S, Thommen M, Mittelstaet J, Kutz F, Schwalbe* H, Rodnina* M, Komar* A.  2016.  Synonymous codons direct co-translational folding towards different proteins conformations. Mol. Cell. 61(3):341-51.
Chauhan A, Paul R, Debnath M, Bessi I, Mandal S, Schwalbe H, Dash J.  2016.  Synthesis of Fluorescent Binaphthyl Amines That Bind c-MYC G-Quadruplex DNA and Repress c-MYC Expression.. J Med Chem. 59:7275-81.
Andernach L, Sandjo L, Liermann J, Schlämann R, Richter C, Ferner J-P, Schwalbe H, Schueffler A, Thines E, Opatz T.  2016.  Terphenyl Derivatives from Allantophomopsis lycopodina. J. Natural Product. 79:2718-2725.
Wirmer-Bartoschek J, Schwalbe H.  2016.  Understanding how DNA enzymes work. Angew. Chem. Int. Ed.. 55(18):5376-7.
2015
Nasiri HR, Ferner J, Tükek C, Krishnathas R, Schwalbe H.  2015.  A concise one-step synthesis of primin and iso-primin. Tetrahedron Lett.. 56:2231-2233.
Buhr F, Kohl-Landgraf J, tom Dieck S, Hanus C, Chatterjee D, Hegelein A, Schuman EM, Wachtveitl J, Schwalbe H.  2015.  Design of photocaged puromycin for nascent polypeptide release and spatiotemporal monitoring of translation. Angew. Chem. Intl. Ed.. 54:3717-21.
Silvers R, Keller H, Schwalbe H, Hengesbach M.  2015.  Differential Scanning Fluorimetry for Monitoring RNA Stability. ChemBioChem. 16:1109–1114.
Barthelmes D, Gränz M, Barthelmes K, Allen KN, Imperiali B, Prisner T, Schwalbe H.  2015.  Encoded Loop-Lanthanide-Binding Tags for Long-Range Distance Measurements in Proteins by NMR and EPR Spectroscopy. J. Biomol. NMR. 63(3):275-82.
Baldus-Becker J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H et al..  2015.  Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci USA. 112(32):9896-901.
Ardenkjaer-Larsen J-H, Boebinger GS, Comment A, Duckett S, Edison A, Engelke F, Griesinger C, Griffin RG, Hilty C, Maeda H et al..  2015.  Facing and Overcoming Biomolecular NMR’s sensitivity challenges. Angew. Chem. Intl. Ed.. 54:9162-85.
Göbel M, Schwalbe H.  2015.  Gerhard Quinkert (1927-2015). Angew, Chem. Int. Ed. . 54:8597.
Kudlinzki D, Linhard VL, Saxena K, Sreeramulu S, Gande S, Schieborr U, Dreyer M, Schwalbe H.  2015.  High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.. Acta Crystallogr F Struct Biol Commun.. 71:1088-93.
D.Chatterjee, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H.  2015.  Influence of arrestin on the photodecay of bovine rhodopsin. Angew, Chem. Int. Ed.. 54:13555-13560.
Rehbein P, Schwalbe H.  2015.  Integrated protocol for reliable and fast quantification and documentation of electrophoresis gels. Protein Expr Purif.. 2015(110):1-6.
Bessi I, Jonker HRA, Richter C, Schwalbe H.  2015.  Involvement of Long-Lived Intermediate States in the Complex Folding Pathway of the Human Telomeric G-Quadruplex. Angew. Chem. Intl. Ed.. 54:8444-8448.
Zickermann V, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Brandt U.  2015.  Mechanistic insight from the crystal structure of mitochondrial complex I. Science. 347(6217):44-49.
Wagner D, Rinnenthal J, Narberhaus F, Schwalbe H.  2015.  Mechanistic insights into temperature-dependent regulation of the simple cyanobacterial hsp17 RNA thermometer at base pair-resolution. Nucl. Acids Res. 43:5572-5585.
Danne L, Aktas M, Gleichenhagen J, Grund N, Wagner D, Schwalbe H, Hoffknecht B, Metzler-Nolte N, Narberhaus F.  2015.  Membrane binding mechanism of a bacterial phospholipid N-methyltransferase. Molecular Microbiology . 95(2):313-331.
Fürtig B, Nozinovic S, Reining A, Schwalbe H.  2015.  Multiple conformational states of riboswitches fine-tune gene regulation. Curr. Opin. Struct. Biol.. 30:112-124.
Panda D, Debnath M, Mandal S, Bessi I, Schwalbe H, Dash J.  2015.  A Nucleus-Imaging Probe That Selectively Stabilizes a Minor Conformation of c-MYC G-quadruplex and Down-regulates c-MYC Transcription in Human Cancer Cells. Scientific Reports. 5:13183.
Scharow A, Raab M, Saxena K, Sreeramulu S, Kudlinzki D, Gande S, Dötsch C, Kurunci-Csacsko E, Kläger S, Küster B et al..  2015.  Optimized Plk1 PBD inhibitors based on Poloxin induce mitotic arrest and apoptosis in tumor cells. ACS Chemical Biology. 10(11):2570-9.
Toal S, Kubatova N, Richter C, Linhardt V, Schwalbe H, Schweitzer-Stenner R.  2015.  Randomizing the unfolded state of peptides (and proteins) by nearest neighbor interactions between unlike residues. Chemistry. 21(13):5173-5192.
Helmling C, Keyhani S, Sochor F, Fürtig B, Hengesbach M, Schwalbe H.  2015.  Rapid NMR screening of RNA secondary structure and binding. J. Biomol. NMR. 63(1):67-76.
Saxena K, Schwalbe H.  2015.  The role of NMR in target identification and validation for pharmaceutical R&D. 4:305-314..
Bruns N, Collisi W, Bernecker S, Stadler M, Richter C, Schwalbe H, Kalesse M.  2015.  Spirangien Derivatives from the Myxobacterium Sorangium cellulosum: Isolation, Structure Elucidation, and Biological Activity. European Journal of Organic Chemistry. 4:847-857.
Chatterjee D, Kudlinzki D, Linhard V, Saxena K, Schieborr U, Gande SL, Wurm JP, Wöhnert J, Abele R, Rogov VV et al..  2015.  Structure and Biophysical Characterization of the S-adenosylmethionine Dependent O-methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J. Biol. Chem.. 290:16415-30.
Schimming O, Challinor VL, Tobias NJ, Adihou H, Grün P, Pöschel L, Richter C, Schwalbe H, Bode HB.  2015.  Structure, Biosynthesis, and Occurence of Bacterial Pyrrolizidine Alkaloids. Angew. Chem. Intl. Ed.. 54:12702-5.
Rinnenthal J, Wagner D, Marquardsen T, Krahn A, Engelke F, Schwalbe H.  2015.  A temperature-jump NMR probe setup using rf heating optimized for the analysis of temperature-induced biomacromolecular kinetics processes. J. Magn. Reson.. 251C:84-93.
Lannes L, Halder S, Krishnan Y, Schwalbe H.  2015.  Tuning the pH-response of i-motif DNA oligonucleotides. ChemBioChem. 16(11):1647-56.
Özçoban C, Halbritter T, Steinwand S, Herzig L-M, Kohl-Landgraf J, Askari N, Groher F, Fuertig B, Richter C, Schwalbe H et al..  2015.  Water-Soluble Py-BIPS Spiropyrans as Photoswitches for Biological Applications. Organic Letters. 17(6):1517-20.
2014
Schwalbe H.  2014.  Author Profile Harald Schwalbe. Angew. Chem. Int Ed Engl.. 53:10576–10577.
Fürtig B, Reining A, Sochor F, Oberhauser EM, Heckel A, Schwalbe H.  2014.  Characterization of the conformational dynamics of bistable RNAs by equilibrium and non-equilibrium NMR methods. Current Protocols in Nucleic Acid Chemistry. 55