Publications

Found 450 results

2008
Nören-Müller A, Wilk W, Saxena K, Schwalbe H, Kaiser M, Waldmann H.  2008.  Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis.. Angew Chem Int Ed Engl. 47:5973–5977.
Nasiri HR, Bolte M, Schwalbe H.  2008.  Electrochemical and crystal structural analysis of alpha- and dehydro-alpha-lapachones.. Nat Prod Res. 22:1225–1230. Abstract
Nielsen G, Stadler M, Jonker HRA, Betz M, Schwalbe H.  2008.  NMR Spectroscopy in Chemical Biology. Encyclopedia in Chemical Biology.
Fürtig B, Richter C, Schell P, Wenter P, Pitsch S, Schwalbe H.  2008.  NMR-spectroscopic characterization of phosphodiester bond cleavage catalyzed by the minimal hammerhead ribozyme.. RNA Biol. 5:41–48. Abstract
Fürtig B, Schwalbe H.  2008.  Nucleic Acids from A to Z. Nucleic Acids from A to Z. :185-200. Abstract
Lopez JJ, Shukla AK, Reinhart C, Schwalbe H, Michel H, Glaubitz C.  2008.  The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy.. Angew Chem Int Ed Engl. 47:1668–1671.
2007
Corrêa IR, Nören-Müller A, Ambrosi H-D, Jakupovic S, Saxena K, Schwalbe H, Kaiser M, Waldmann H.  2007.  Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS).. Chem Asian J. 2:1109–1126. Abstract
Rinnenthal J, Richter C, Ferner J, Duchardt E, Schwalbe H.  2007.  Quantitative gamma-HCNCH: determination of the glycosidic torsion angle chi in RNA oligonucleotides from the analysis of CH dipolar cross-correlated relaxation by solution NMR spectroscopy.. J Biomol NMR. 39:17–29. Abstract
Obolensky OI, Schlepckow K, Schwalbe H, Solov'yov AV.  2007.  Theoretical framework for NMR residual dipolar couplings in unfolded proteins.. J Biomol NMR. 39:1–16. Abstract
Buck J, Fürtig B, Noeske J, Wöhnert J, Schwalbe H.  2007.  Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution.. Proc Natl Acad Sci U S A. 104:15699–15704. Abstract
Ludwig V, Krebs A, Stoll M, Dietrich U, Ferner J, Schwalbe H, Scheffer U, Dürner G, Göbel MW.  2007.  Tripeptides from synthetic amino acids block the Tat-TAR association and slow down HIV spread in cell cultures.. Chembiochem. 8:1850–1856. Abstract
Haber-Pohlmeier S, Abarca-Heidemann K, Körschen HG, Dhiman KH, Heberle J, Schwalbe H, Klein-Seetharaman J, Kaupp UB, Pohlmeier A.  2007.  Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment.. Biophys J. 92:3207–3214. Abstract
Duchardt E, Sigalov AB, Aivazian D, Stern LJ, Schwalbe H.  2007.  Structure induction of the T-cell receptor zeta-chain upon lipid binding investigated by NMR spectroscopy.. Chembiochem. 8:820–827. Abstract
Silvaggi NR, Martin LJ, Schwalbe H, Imperiali B, Allen KN.  2007.  Double-lanthanide-binding tags for macromolecular crystallographic structure determination.. J Am Chem Soc. 129:7114–7120. Abstract
Martin LJ, Hähnke MJ, Nitz M, Wöhnert J, Silvaggi NR, Allen KN, Schwalbe H, Imperiali B.  2007.  Double-lanthanide-binding tags: design, photophysical properties, and NMR applications.. J Am Chem Soc. 129:7106–7113. Abstract
Graf J, Nguyen PH, Stock G, Schwalbe H.  2007.  Structure and dynamics of the homologous series of alanine peptides: a joint molecular dynamics/NMR study.. J Am Chem Soc. 129:1179–1189. Abstract
Fürtig B, Wenter P, Reymond L, Richter C, Pitsch S, Schwalbe H.  2007.  Conformational dynamics of bistable RNAs studied by time-resolved NMR spectroscopy.. J Am Chem Soc. 129:16222–16229. Abstract
Werner K, Lehner I, Dhiman HK, Richter C, Glaubitz C, Schwalbe H, Klein-Seetharaman J, Khorana GH.  2007.  Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin.. J Biomol NMR. 37:303–312. Abstract
Noeske J, Buck J, Fürtig B, Nasiri HR, Schwalbe H, Wöhnert J.  2007.  Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch.. Nucleic Acids Res. 35:572–583. Abstract
Jonker HRA, Ilin S, Grimm KS, Wöhnert J, Schwalbe H.  2007.  L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy.. Nucleic Acids Res. 35:441–454. Abstract
Noeske J, Schwalbe H, Wöhnert J.  2007.  Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain.. Nucleic Acids Res. 35:5262–5273. Abstract
Schwalbe H, Buck J, Fürtig B, Noeske J, Wöhnert J.  2007.  Structures of RNA switches: insight into molecular recognition and tertiary structure.. Angew Chem Int Ed Engl. 46:1212–1219. Abstract
Fürtig B, Buck J, Manoharan V, Bermel W, Jäschke A, Wenter P, Pitsch S, Schwalbe H.  2007.  Time-resolved NMR studies of RNA folding.. Biopolymers. 86:360–383. Abstract
2006
Noeske J, Richter C, Stirnal E, Schwalbe H, Wöhnert J.  2006.  Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch.. Chembiochem. 7:1451–1456. Abstract
Madej GM, Nasiri HR, Hilgendorff NS, Schwalbe H, Lancaster RCD.  2006.  Evidence for transmembrane proton transfer in a dihaem-containing membrane protein complex.. EMBO J. 25:4963–4970. Abstract
Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dötsch V, Engelke F, Folkers GE et al..  2006.  NMR in the SPINE Structural Proteomics project.. Acta Crystallogr D Biol Crystallogr. 62:1150–1161. Abstract
Wenter P, Fürtig B, Hainard A, Schwalbe H, Pitsch S.  2006.  A caged uridine for the selective preparation of an RNA fold and determination of its refolding kinetics by real-time NMR.. Chembiochem. 7:417–420.
Landrieu I, Lacosse L, Leroy A, Wieruszeski J-M, Trivelli X, Sillen A, Sibille N, Schwalbe H, Saxena K, Langer T et al..  2006.  NMR analysis of a Tau phosphorylation pattern.. J Am Chem Soc. 128:3575–3583. Abstract
Cramer N, Buchweitz M, Laschat S, Frey W, Baro A, Mathieu D, Richter C, Schwalbe H.  2006.  Total synthesis and NMR investigations of cylindramide.. Chemistry. 12:2488–2503. Abstract
Betz M, Saxena K, Schwalbe H.  2006.  Biomolecular NMR: a chaperone to drug discovery.. Curr Opin Chem Biol. 10:219–225. Abstract
Wirmer J, Berk H, Ugolini R, Redfield C, Schwalbe H.  2006.  Characterization of the unfolded state of bovine alpha-lactalbumin and comparison with unfolded states of homologous proteins.. Protein Sci. 15:1397–1407. Abstract
Wirmer J, Peti W, Schwalbe H.  2006.  Motional properties of unfolded ubiquitin: a model for a random coil protein.. J Biomol NMR. 35:175–186. Abstract
Batra-Safferling R, Abarca-Heidemann K, Körschen HG, Tziatzios C, Stoldt M, Budyak I, Willbold D, Schwalbe H, Klein-Seetharaman J, Kaupp BU.  2006.  Glutamic acid-rich proteins of rod photoreceptors are natively unfolded.. J Biol Chem. 281:1449–1460. Abstract
Vogtherr M, Saxena K, Hoelder S, Grimme S, Betz M, Schieborr U, Pescatore B, Robin M, Delarbre L, Langer T et al..  2006.  NMR characterization of kinase p38 dynamics in free and ligand-bound forms.. Angew Chem Int Ed Engl. 45:993–997.
Schlörb C, Mensch S, Richter C, Schwalbe H.  2006.  Photo-CIDNP reveals differences in compaction of non-native states of lysozyme.. J Am Chem Soc. 128:1802–1803. Abstract
Nasiri HR, Madej GM, Lancaster RCD, Schwalbe H, Bolte M.  2006.  2-Hydroxy-3-(3-oxobutyl)naphthalene-1,4-dione.. Acta Crystallogr C. 62:o671–o673. Abstract
Madej GM, Nasiri HR, Hilgendorff NS, Schwalbe H, Unden G, Lancaster RCD.  2006.  Experimental evidence for proton motive force-dependent catalysis by the diheme-containing succinate:menaquinone oxidoreductase from the Gram-positive bacterium Bacillus licheniformis.. Biochemistry. 45:15049–15055. Abstract
Müller D, Krick A, Kehraus S, Mehner C, Hart M, Küpper FC, Saxena K, Prinz H, Schwalbe H, Janning P et al..  2006.  Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.. J Med Chem. 49:4871–4878. Abstract
Raja C, Ferner J, Dietrich U, Avilov S, Ficheux D, Darlix J-L, de Rocquigny H, Schwalbe H, Mély Y.  2006.  A tryptophan-rich hexapeptide inhibits nucleic acid destabilization chaperoned by the HIV-1 nucleocapsid protein.. Biochemistry. 45:9254–9265. Abstract
Rehm S, Lenz MO, Mensch S, Schwalbe H, Wachtveitl J.  2006.  Ultrafast spectroscopy of a photoswitchable 30-amino acid de novo synthesized peptide. Nonequilibrium Dynamics in Biomolecules. 323(1):28-35. Abstract
Nören-Müller A, Reis-Corrêa I, Prinz H, Rosenbaum C, Saxena K, Schwalbe HJ, Vestweber D, Cagna G, Schunk S, Schwarz O et al..  2006.  Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proceedings of the National Academy of Sciences. 103(28):10606-10611. Abstract
Betz M, Vogtherr M, Schieborr U, Elshorst B, Grimme S, Pescatore B, Langer T, Saxena K, Schwalbe H.  2006.  Chemical Biology of Kinases Studied by NMR Spectroscopy. Chemical Biology - From Small Molecules to Systems Biology and Drug Design.
Nasiri HR, Bolte M, Lorch M, Schwalbe H.  2006.  Crystal structure of 4-hexyl-4'-hydroxyazobenzene isopropanol hemisolvate, C18H22N2O · ½C3H8O. Z. Kristallogr. NCS. 221:219-220.
[Anonymous].  2006.  Isoguanine dihydro­chloride dihydrate. Acta Crystallographica Section E. 62(5):o2040-o2042. Abstract
Jacobs DM, Langer T, Elshorst B, Saxena K, Fiebig KM, Vogtherr M, Schwalbe H.  2006.  NMR backbone assignment of the N-terminal domain of human HSP90.. J Biomol NMR. 36 Suppl 1:52.
Nasiri HR, Bolte M, Schwalbe H.  2006.  Tautomerism of 4-Hydroxy-4(1H) quinolon. Heterocyclic Communications. 12
2005
Collins ES, Wirmer J, Hirai K, Tachibana H, Segawa S-ichi, Dobson CM, Schwalbe H.  2005.  Characterisation of disulfide-bond dynamics in non-native states of lysozyme and its disulfide deletion mutants by NMR.. Chembiochem. 6:1619–1627. Abstract
Ilin S, Hoskins A, Ohlenschläger O, Jonker HRA, Schwalbe H, Wöhnert J.  2005.  Domain reorientation and induced fit upon RNA binding: solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima.. Chembiochem. 6:1611–1618. Abstract
Koplin J, Mu Y, Richter C, Schwalbe H, Stock G.  2005.  Structure and dynamics of an RNA tetraloop: a joint molecular dynamics and NMR study.. Structure. 13:1255–1267. Abstract
Saxena K, Elshorst B, Berk H, Betz M, Grimme S, Langer T, Pescatore B, Schieborr U, Vogtherr M, Schwalbe H.  2005.  Backbone NMR assignment of the low-molecular-weight protein tyrosine phosphatase (MPtpA) from Mycobacterium tuberculosis.. J Biomol NMR. 33:136.