Publications

Found 450 results

2005
Manger M, Scheck M, Prinz H, von Kries JP, Langer T, Saxena K, Schwalbe H, Fürstner A, Rademann J, Waldmann H.  2005.  Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.. Chembiochem. 6:1749–1753.
Schlörb C, Ackermann K, Richter C, Wirmer J, Schwalbe H.  2005.  Heterologous expression of hen egg white lysozyme and resonance assignment of tryptophan side chains in its non-native states.. J Biomol NMR. 33:95–104. Abstract
Schieborr U, Vogtherr M, Elshorst B, Betz M, Grimme S, Pescatore B, Langer T, Saxena K, Schwalbe H.  2005.  How much NMR data is required to determine a protein-ligand complex structure? Chembiochem. 6:1891–1898. Abstract
Vogtherr M, Saxena K, Grimme S, Betz M, Schieborr U, Pescatore B, Langer T, Schwalbe H.  2005.  NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38.. J Biomol NMR. 32:175.
Sreeramulu S, Kumar J, Richter C, Vogtherr M, Saxena K, Langer T, Schwalbe H.  2005.  1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37.. J Biomol NMR. 32:262.
Cramer N, Laschat S, Baro A, Schwalbe H, Richter C.  2005.  Enantioselective total synthesis of cylindramide.. Angew Chem Int Ed Engl. 44:820–822.
Noeske J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, Wöhnert J.  2005.  An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs.. Proc Natl Acad Sci U S A. 102:1372–1377. Abstract
Lancaster RCD, Sauer US, Gross R, Haas AH, Graf J, Schwalbe H, Mäntele W, Simon J, Madej GM.  2005.  Experimental support for the "E pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol:fumarate reductase.. Proc Natl Acad Sci U S A. 102:18860–18865. Abstract
Jacobs DM, Grimme S, Elshorst B, Pescatore B, Vogtherr M, Betz M, Schieborr U, Langer T, Saxena K, Schwalbe H et al..  2005.  Backbone NMR assignment of the C-terminal haemopexin-like domain (HPLD) of human matrix metalloproteinase MMP-13.. J Biomol NMR. 32:337.
Saxena K, Jacobs DM, Vogtherr M, Grimme S, Elshort B, Pescatore B, Betz M, Schieborr U, Langer T, Schwalbe H et al..  2005.  Backbone NMR assignment of the human E2 ubiquitin conjugating enzyme UbcH5alpha (F72K,F82S) double mutant.. J Biomol NMR. 32:338.
Langer T, Sreeramulu S, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H.  2005.  Folding and activity of cAMP-dependent protein kinase mutants.. FEBS Lett. 579:4049–4054. Abstract
Duchardt E, Schwalbe H.  2005.  Residue specific ribose and nucleobase dynamics of the cUUCGg RNA tetraloop motif by NMR 13C relaxation.. J Biomol NMR. 32:295–308. Abstract
Wenter P, Fürtig B, Hainard A, Schwalbe H, Pitsch S.  2005.  Kinetics of photoinduced RNA refolding by real-time NMR spectroscopy.. Angew Chem Int Ed Engl. 44:2600–2603.
Bertini I, Gupta YK, Luchinat C, Parigi G, Schlörb C, Schwalbe H.  2005.  NMR spectroscopic detection of protein protons and longitudinal relaxation rates between 0.01 and 50 MHz.. Angew Chem Int Ed Engl. 44:2223–2225.
Nasiri, Hamid Reza, Schwalbe, Harald, Bolte, Michael, Wohnert, Jens.  2005.  N9,N7-Dimethylhypoxanthinium iodide. 61(10):o3353-o3354. Abstract
Wirmer J, Schlörb C, Schwalbe H.  2005.  Conformation and Dynamics of Nonnative States of Proteins studied by NMR Spectroscopy. Protein Folding Handbook. :737-808. Abstract
Schwalbe H, Stilz HU, Kessler H.  2005.  Editorial: NMR Spectroscopy of Biomacromolecules in Drug Discovery and Beyond. ChemBioChem. 6(9):1475-1478. Abstract
Nozinovic S, Nachtsheim B, Scheuermann S, Schnorr J, Silvers R, Wagner M, Schwalbe H.  2005.  Learning problem-solving thinking in group work. Nachrichten aus der Chemie. 53:978-980.
Schwalbe H, Wirmer J.  2005.  Protein Misfolding Disease: Overview of liquid and solid state high resolution NMR studies. Handbook of Modern Magnetic Resonance.
2004
Giroglou T, Cinatl J, Rabenau H, Drosten C, Schwalbe H, Doerr HW, von Laer D.  2004.  Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein.. J Virol. 78:9007–9015. Abstract
Schwalbe H, Wess G.  2004.  Molecules as modulators: systems biology challenges chemistry.. Chembiochem. 5:1311–1313.
Wirmer J, Schlörb C, Klein-Seetharaman J, Hirano R, Ueda T, Imoto T, Schwalbe H.  2004.  Modulation of compactness and long-range interactions of unfolded lysozyme by single point mutations.. Angew Chem Int Ed Engl. 43:5780–5785.
Langer T, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H.  2004.  NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase.. Chembiochem. 5:1508–1516. Abstract
Fürtig B, Richter C, Bermel W, Schwalbe H.  2004.  New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop.. J Biomol NMR. 28:69–79.
van Buuren BNM, Schleucher J, Wittmann V, Griesinger C, Schwalbe H, Wijmenga SS.  2004.  NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides.. Angew Chem Int Ed Engl. 43:187–192.
Duchardt E, Richter C, Ohlenschläger O, Görlach M, Wöhnert J, Schwalbe H.  2004.  Determination of the glycosidic bond angle chi in RNA from cross-correlated relaxation of CH dipolar coupling and N chemical shift anisotropy.. J Am Chem Soc. 126:1962–1970. Abstract
Klein-Seetharaman J, Yanamala NVK, Javeed F, Reeves PJ, Getmanova EV, Loewen MC, Schwalbe H, Khorana GH.  2004.  Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR. Proceedings of the National Academy of Sciences of the United States of America. 101(10):3409-3413. Abstract
2003
Elshorst B, Jacobs DM, Schwalbe H, Langer T.  2003.  1H, 13C and 15N backbone resonance assignment of the integrin alpha2 I-domain.. J Biomol NMR. 27:191–192.
Vogtherr M, Grimme S, Pescatore B, Schwalbe H.  2003.  1H, 13C and 15N backbone resonance assignment of the VASP EVH1 domain.. J Biomol NMR. 27:189–190.
Pustowka A, Dietz J, Ferner J, Baumann M, Landersz M, Königs C, Schwalbe H, Dietrich U.  2003.  Identification of peptide ligands for target RNA structures derived from the HIV-1 packaging signal psi by screening phage-displayed peptide libraries.. Chembiochem. 4:1093–1097.
Fürtig B, Richter C, Wöhnert J, Schwalbe H.  2003.  NMR spectroscopy of RNA.. Chembiochem. 4:936–962. Abstract
Wöhnert J, Franz KJ, Nitz M, Imperiali B, Schwalbe H.  2003.  Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings.. J Am Chem Soc. 125:13338–13339. Abstract
Wöhnert J, Görlach M, Schwalbe H.  2003.  Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules.. J Biomol NMR. 26:79–83. Abstract
Ilin S, Bosques C, Turner C, Schwalbe H.  2003.  Gamma-HMBC: an NMR experiment for the conformational analysis of the o-glycosidic linkage in glycopeptides.. Angew Chem Int Ed Engl. 42:1394–1397.
Schwalbe H.  2003.  Kurt Wüthrich, the ETH Zürich, and the development of NMR spectroscopy for the investigation of structure, dynamics, and folding of proteins.. Chembiochem. 4:135–142.
Ilin S, Hoskins A, Schwalbe H, Wöhnert J.  2003.  NMR assignment of the full-length ribosomal protein L11 from Thermotoga maritima.. J Biomol NMR. 25:163–164.
Schwalbe H, Kessler H.  2003.  900-MHz-NMR-Spektrometer in München und Frankfurt. Nachrichten aus der Chemie. 51
Schwalbe H, Göbel M, Wess G.  2003.  Editorial: RNA Targeting. ChemBioChem. 4(10):915-917. Abstract
2002
Klein-Seetharaman J, Oikawa M, Grimshaw SB, Wirmer J, Duchardt E, Ueda T, Imoto T, Smith LJ, Dobson CM, Schwalbe H.  2002.  Long-range interactions within a nonnative protein.. Science. 295:1719–1722. Abstract
Klein-Seetharaman J, Reeves PJ, Loewen MC, Getmanova EV, Chung J, Schwalbe H, Wright PE, Khorana HG.  2002.  Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence.. Proc Natl Acad Sci U S A. 99:3452–3457. Abstract
Ilin S, Schlönvogt I, Ebert M-O, Jaun B, Schwalbe H.  2002.  Comparison of the NMR spectroscopy solution structures of pyranosyl-rNA and its nucleo-delta-peptide analogue.. Chembiochem. 3:93–99. Abstract
Wirmer J, Schwalbe H.  2002.  Angular dependence of 1J(Ni,Cα i) and 2J(Ni,Cα (i − 1)) coupling constants measured in J-modulated HSQCs. Journal of Biomolecular NMR. 23(1):47-55. Abstract
Griesinger C, Hennig M, Marino J, Reif B, Richter C, Schwalbe H.  2002.  Methods for the Determination of Torsion Angle Restraints in Biomacromolecules. Modern Techniques in Protein NMR. :259-367.
Schwalbe H, Wess G.  2002.  Editorial: Dissecting G-Protein-Coupled Receptors: Structure, Function, and Ligand Interaction. ChemBioChem. 3(10):915-919.
Peter, Fred, Lukas, Wilfred, Duchardt E, Schwalbe H, Albert M, Seebach D.  2002.  A Molecular-Dynamics Simulation Study of the Conformational Preferences of Oligo(3-hydroxyalkanoic acids) in Chloroform Solution. Helvetica Chimica Acta. 85(2):618-632. Abstract
Albert M, Seebach D, Duchardt E, Schwalbe H.  2002.  Synthesis and NMR Analysis in Solution of Oligo(3-hydroxyalkanoic acid) Derivatives with the Side Chains of Alanine, Valine, and Leucine (β-Depsides): Coming Full Circle from PHB to β-Peptides to PHB. Helvetica Chimica Acta. 85(2):633-658. Abstract
Anastasiadis-Pool A, Schwalbe H.  2002.  Web Site: Web Sites about G-Protein-Coupled Receptors. ChemBioChem. 3(10):1029-1030. Abstract
2001
Duchardt E, Richter C, Reif B, Glaser SJ, Engels JW, Griesinger C, Schwalbe H.  2001.  Measurement of 2J(H,C)- and 3J(H,C)-coupling constants by alpha/beta selective HC(C)H-TOCSY.. J Biomol NMR. 21:117–126. Abstract
Peti W, Smith LJ, Redfield C, Schwalbe H.  2001.  Chemical shifts in denatured proteins: resonance assignments for denatured ubiquitin and comparisons with other denatured proteins.. J Biomol NMR. 19:153–165. Abstract
Smith CK, Wöhnert J, Sauer RT, Schwalbe H.  2001.  Assignments of the 1H,13C, and 15N resonances of the substrate-binding SSD domain from Lon protease.. J Biomol NMR. 21:387–388.