Publications

Found 229 results

2006
Madej GM, Nasiri HR, Hilgendorff NS, Schwalbe H, Unden G, Lancaster RCD.  2006.  Experimental evidence for proton motive force-dependent catalysis by the diheme-containing succinate:menaquinone oxidoreductase from the Gram-positive bacterium Bacillus licheniformis.. Biochemistry. 45:15049–15055. Abstract
Müller D, Krick A, Kehraus S, Mehner C, Hart M, Küpper FC, Saxena K, Prinz H, Schwalbe H, Janning P et al..  2006.  Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.. J Med Chem. 49:4871–4878. Abstract
Raja C, Ferner J, Dietrich U, Avilov S, Ficheux D, Darlix J-L, de Rocquigny H, Schwalbe H, Mély Y.  2006.  A tryptophan-rich hexapeptide inhibits nucleic acid destabilization chaperoned by the HIV-1 nucleocapsid protein.. Biochemistry. 45:9254–9265. Abstract
Rehm S, Lenz MO, Mensch S, Schwalbe H, Wachtveitl J.  2006.  Ultrafast spectroscopy of a photoswitchable 30-amino acid de novo synthesized peptide. Nonequilibrium Dynamics in Biomolecules. 323(1):28-35. Abstract
Betz M, Vogtherr M, Schieborr U, Elshorst B, Grimme S, Pescatore B, Langer T, Saxena K, Schwalbe H.  2006.  Chemical Biology of Kinases Studied by NMR Spectroscopy. Chemical Biology - From Small Molecules to Systems Biology and Drug Design.
Nasiri HR, Bolte M, Lorch M, Schwalbe H.  2006.  Crystal structure of 4-hexyl-4'-hydroxyazobenzene isopropanol hemisolvate, C18H22N2O · ½C3H8O. Z. Kristallogr. NCS. 221:219-220.
Jacobs DM, Langer T, Elshorst B, Saxena K, Fiebig KM, Vogtherr M, Schwalbe H.  2006.  NMR backbone assignment of the N-terminal domain of human HSP90.. J Biomol NMR. 36 Suppl 1:52.
Nasiri HR, Bolte M, Schwalbe H.  2006.  Tautomerism of 4-Hydroxy-4(1H) quinolon. Heterocyclic Communications. 12
2005
Collins ES, Wirmer J, Hirai K, Tachibana H, Segawa S-ichi, Dobson CM, Schwalbe H.  2005.  Characterisation of disulfide-bond dynamics in non-native states of lysozyme and its disulfide deletion mutants by NMR.. Chembiochem. 6:1619–1627. Abstract
Ilin S, Hoskins A, Ohlenschläger O, Jonker HRA, Schwalbe H, Wöhnert J.  2005.  Domain reorientation and induced fit upon RNA binding: solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima.. Chembiochem. 6:1611–1618. Abstract
Koplin J, Mu Y, Richter C, Schwalbe H, Stock G.  2005.  Structure and dynamics of an RNA tetraloop: a joint molecular dynamics and NMR study.. Structure. 13:1255–1267. Abstract
Saxena K, Elshorst B, Berk H, Betz M, Grimme S, Langer T, Pescatore B, Schieborr U, Vogtherr M, Schwalbe H.  2005.  Backbone NMR assignment of the low-molecular-weight protein tyrosine phosphatase (MPtpA) from Mycobacterium tuberculosis.. J Biomol NMR. 33:136.
Manger M, Scheck M, Prinz H, von Kries JP, Langer T, Saxena K, Schwalbe H, Fürstner A, Rademann J, Waldmann H.  2005.  Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.. Chembiochem. 6:1749–1753.
Schlörb C, Ackermann K, Richter C, Wirmer J, Schwalbe H.  2005.  Heterologous expression of hen egg white lysozyme and resonance assignment of tryptophan side chains in its non-native states.. J Biomol NMR. 33:95–104. Abstract
Schieborr U, Vogtherr M, Elshorst B, Betz M, Grimme S, Pescatore B, Langer T, Saxena K, Schwalbe H.  2005.  How much NMR data is required to determine a protein-ligand complex structure? Chembiochem. 6:1891–1898. Abstract
Vogtherr M, Saxena K, Grimme S, Betz M, Schieborr U, Pescatore B, Langer T, Schwalbe H.  2005.  NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38.. J Biomol NMR. 32:175.
Sreeramulu S, Kumar J, Richter C, Vogtherr M, Saxena K, Langer T, Schwalbe H.  2005.  1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37.. J Biomol NMR. 32:262.
Cramer N, Laschat S, Baro A, Schwalbe H, Richter C.  2005.  Enantioselective total synthesis of cylindramide.. Angew Chem Int Ed Engl. 44:820–822.
Noeske J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, Wöhnert J.  2005.  An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs.. Proc Natl Acad Sci U S A. 102:1372–1377. Abstract
Lancaster RCD, Sauer US, Gross R, Haas AH, Graf J, Schwalbe H, Mäntele W, Simon J, Madej GM.  2005.  Experimental support for the "E pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol:fumarate reductase.. Proc Natl Acad Sci U S A. 102:18860–18865. Abstract
Jacobs DM, Grimme S, Elshorst B, Pescatore B, Vogtherr M, Betz M, Schieborr U, Langer T, Saxena K, Schwalbe H et al..  2005.  Backbone NMR assignment of the C-terminal haemopexin-like domain (HPLD) of human matrix metalloproteinase MMP-13.. J Biomol NMR. 32:337.
Saxena K, Jacobs DM, Vogtherr M, Grimme S, Elshort B, Pescatore B, Betz M, Schieborr U, Langer T, Schwalbe H et al..  2005.  Backbone NMR assignment of the human E2 ubiquitin conjugating enzyme UbcH5alpha (F72K,F82S) double mutant.. J Biomol NMR. 32:338.
Langer T, Sreeramulu S, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H.  2005.  Folding and activity of cAMP-dependent protein kinase mutants.. FEBS Lett. 579:4049–4054. Abstract
Duchardt E, Schwalbe H.  2005.  Residue specific ribose and nucleobase dynamics of the cUUCGg RNA tetraloop motif by NMR 13C relaxation.. J Biomol NMR. 32:295–308. Abstract
Wenter P, Fürtig B, Hainard A, Schwalbe H, Pitsch S.  2005.  Kinetics of photoinduced RNA refolding by real-time NMR spectroscopy.. Angew Chem Int Ed Engl. 44:2600–2603.
Bertini I, Gupta YK, Luchinat C, Parigi G, Schlörb C, Schwalbe H.  2005.  NMR spectroscopic detection of protein protons and longitudinal relaxation rates between 0.01 and 50 MHz.. Angew Chem Int Ed Engl. 44:2223–2225.
Wirmer J, Schlörb C, Schwalbe H.  2005.  Conformation and Dynamics of Nonnative States of Proteins studied by NMR Spectroscopy. Protein Folding Handbook. :737-808. Abstract
Schwalbe H, Stilz HU, Kessler H.  2005.  Editorial: NMR Spectroscopy of Biomacromolecules in Drug Discovery and Beyond. ChemBioChem. 6(9):1475-1478. Abstract
Nozinovic S, Nachtsheim B, Scheuermann S, Schnorr J, Silvers R, Wagner M, Schwalbe H.  2005.  Learning problem-solving thinking in group work. Nachrichten aus der Chemie. 53:978-980.
Schwalbe H, Wirmer J.  2005.  Protein Misfolding Disease: Overview of liquid and solid state high resolution NMR studies. Handbook of Modern Magnetic Resonance.
2004
Giroglou T, Cinatl J, Rabenau H, Drosten C, Schwalbe H, Doerr HW, von Laer D.  2004.  Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein.. J Virol. 78:9007–9015. Abstract
Schwalbe H, Wess G.  2004.  Molecules as modulators: systems biology challenges chemistry.. Chembiochem. 5:1311–1313.
Wirmer J, Schlörb C, Klein-Seetharaman J, Hirano R, Ueda T, Imoto T, Schwalbe H.  2004.  Modulation of compactness and long-range interactions of unfolded lysozyme by single point mutations.. Angew Chem Int Ed Engl. 43:5780–5785.
Langer T, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H.  2004.  NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase.. Chembiochem. 5:1508–1516. Abstract
Fürtig B, Richter C, Bermel W, Schwalbe H.  2004.  New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop.. J Biomol NMR. 28:69–79.
van Buuren BNM, Schleucher J, Wittmann V, Griesinger C, Schwalbe H, Wijmenga SS.  2004.  NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides.. Angew Chem Int Ed Engl. 43:187–192.
Duchardt E, Richter C, Ohlenschläger O, Görlach M, Wöhnert J, Schwalbe H.  2004.  Determination of the glycosidic bond angle chi in RNA from cross-correlated relaxation of CH dipolar coupling and N chemical shift anisotropy.. J Am Chem Soc. 126:1962–1970. Abstract
Klein-Seetharaman J, Yanamala NVK, Javeed F, Reeves PJ, Getmanova EV, Loewen MC, Schwalbe H, Khorana GH.  2004.  Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR. Proceedings of the National Academy of Sciences of the United States of America. 101(10):3409-3413. Abstract
2003
Elshorst B, Jacobs DM, Schwalbe H, Langer T.  2003.  1H, 13C and 15N backbone resonance assignment of the integrin alpha2 I-domain.. J Biomol NMR. 27:191–192.
Vogtherr M, Grimme S, Pescatore B, Schwalbe H.  2003.  1H, 13C and 15N backbone resonance assignment of the VASP EVH1 domain.. J Biomol NMR. 27:189–190.
Pustowka A, Dietz J, Ferner J, Baumann M, Landersz M, Königs C, Schwalbe H, Dietrich U.  2003.  Identification of peptide ligands for target RNA structures derived from the HIV-1 packaging signal psi by screening phage-displayed peptide libraries.. Chembiochem. 4:1093–1097.
Fürtig B, Richter C, Wöhnert J, Schwalbe H.  2003.  NMR spectroscopy of RNA.. Chembiochem. 4:936–962. Abstract
Wöhnert J, Franz KJ, Nitz M, Imperiali B, Schwalbe H.  2003.  Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings.. J Am Chem Soc. 125:13338–13339. Abstract
Wöhnert J, Görlach M, Schwalbe H.  2003.  Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules.. J Biomol NMR. 26:79–83. Abstract
Ilin S, Bosques C, Turner C, Schwalbe H.  2003.  Gamma-HMBC: an NMR experiment for the conformational analysis of the o-glycosidic linkage in glycopeptides.. Angew Chem Int Ed Engl. 42:1394–1397.
Schwalbe H.  2003.  Kurt Wüthrich, the ETH Zürich, and the development of NMR spectroscopy for the investigation of structure, dynamics, and folding of proteins.. Chembiochem. 4:135–142.
Ilin S, Hoskins A, Schwalbe H, Wöhnert J.  2003.  NMR assignment of the full-length ribosomal protein L11 from Thermotoga maritima.. J Biomol NMR. 25:163–164.
Schwalbe H, Kessler H.  2003.  900-MHz-NMR-Spektrometer in München und Frankfurt. Nachrichten aus der Chemie. 51
Schwalbe H, Göbel M, Wess G.  2003.  Editorial: RNA Targeting. ChemBioChem. 4(10):915-917. Abstract
2002
Klein-Seetharaman J, Oikawa M, Grimshaw SB, Wirmer J, Duchardt E, Ueda T, Imoto T, Smith LJ, Dobson CM, Schwalbe H.  2002.  Long-range interactions within a nonnative protein.. Science. 295:1719–1722. Abstract