Publications

Found 108 results

2015
Barthelmes D, Gränz M, Barthelmes K, Allen KN, Imperiali B, Prisner T, Schwalbe H.  2015.  Encoded Loop-Lanthanide-Binding Tags for Long-Range Distance Measurements in Proteins by NMR and EPR Spectroscopy. J. Biomol. NMR. 63(3):275-82.
Baldus-Becker J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H et al..  2015.  Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci USA. 112(32):9896-901.
Ardenkjaer-Larsen J-H, Boebinger GS, Comment A, Duckett S, Edison A, Engelke F, Griesinger C, Griffin RG, Hilty C, Maeda H et al..  2015.  Facing and Overcoming Biomolecular NMR’s sensitivity challenges. Angew. Chem. Intl. Ed.. 54:9162-85.
Göbel M, Schwalbe H.  2015.  Gerhard Quinkert (1927-2015). Angew, Chem. Int. Ed. . 54:8597.
Kudlinzki D, Linhard VL, Saxena K, Sreeramulu S, Gande S, Schieborr U, Dreyer M, Schwalbe H.  2015.  High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.. Acta Crystallogr F Struct Biol Commun.. 71:1088-93.
D.Chatterjee, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H.  2015.  Influence of arrestin on the photodecay of bovine rhodopsin. Angew, Chem. Int. Ed.. 54:13555-13560.
Rehbein P, Schwalbe H.  2015.  Integrated protocol for reliable and fast quantification and documentation of electrophoresis gels. Protein Expr Purif.. 2015(110):1-6.
Zickermann V, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Brandt U.  2015.  Mechanistic insight from the crystal structure of mitochondrial complex I. Science. 347(6217):44-49.
Fürtig B, Nozinovic S, Reining A, Schwalbe H.  2015.  Multiple conformational states of riboswitches fine-tune gene regulation. Curr. Opin. Struct. Biol.. 30:112-124.
Scharow A, Raab M, Saxena K, Sreeramulu S, Kudlinzki D, Gande S, Dötsch C, Kurunci-Csacsko E, Kläger S, Küster B et al..  2015.  Optimized Plk1 PBD inhibitors based on Poloxin induce mitotic arrest and apoptosis in tumor cells. ACS Chemical Biology. 10(11):2570-9.
Saxena K, Schwalbe H.  2015.  The role of NMR in target identification and validation for pharmaceutical R&D. 4:305-314..
Bruns N, Collisi W, Bernecker S, Stadler M, Richter C, Schwalbe H, Kalesse M.  2015.  Spirangien Derivatives from the Myxobacterium Sorangium cellulosum: Isolation, Structure Elucidation, and Biological Activity. European Journal of Organic Chemistry. 4:847-857.
Schimming O, Challinor VL, Tobias NJ, Adihou H, Grün P, Pöschel L, Richter C, Schwalbe H, Bode HB.  2015.  Structure, Biosynthesis, and Occurence of Bacterial Pyrrolizidine Alkaloids. Angew. Chem. Intl. Ed.. 54:12702-5.
2014
Schilder J, Löhr F, Schwalbe H, Ubbink M.  2014.  The cytochrome c peroxidase and cytochrome c encounter complex: The other side of the story; see also: corrigendum: FEBS Lett. (2015) 589, 2169.. FEBS Lett.. 588(10):1873-8.
Nozinovic S, Reining A, Kim Y-B, Noeske J, Schlepckow K, Wöhnert J, Schwalbe H.  2014.  The importance of helix P1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain. RNA Biology. 11(5):655-666.
2013
Nasiri H, Madej G, Panisch R, Bats J, Lafontaine M, Lancaster CR, Schwalbe H.  2013.  Design, Synthesis and Biological Testing of Novel Naphthoquinones as Substrate-Based Inhibitors of the Quinol:Fumarate Reductase from Wolinella succinogenes.. J. Med. Chem..
Schweitzer-Stenner R, Hagarmann A, Toal S, Mathieu D, Schwalbe H.  2013.  Disorder and order in unfolded and disordered peptides and proteins: A view derived from tripeptide conformational analysis. I. Tripeptides with long and predominantly hydrophobic side chains.. Proteins. 81:955-967.
Rybka K, Toal SE, D.J.Verbaro, Mathieu D, Schwalbe H, Schweizer-Stenner R.  2013.  Disorder and order in unfolded and disordered peptides and proteins: A view derived from tripeptide conformational analysis. II. tripeptides with short side chains populating asx and β-type like turn conformations.. Proteins. 81:968-983.
Kumar YP, Bhowmik S, Das RN, Bessi I, Paladhi S, Ghosh R, Schwalbe H, Dash J.  2013.  A fluorescent guanosine dinucleoside as a selective switch-on sensor for c-myc G-quadruplex DNA with potent anticancer activities. Chemistry - A European Journal. 19(35):11502-6.
Nielsen G, Jonker HRA, Vajpaj N, Grzesiek S, Schwalbe H.  2013.  Kinase in motion: insights into the dynamic nature of p38alpha by high pressure NMR spectroscopic studies.. ChemBioChem. 14:1799-1806.
Schieborr U, Sreeramulu S, Elshorst B, Maurer M, Saxena K, Kudlinzki D, Gande S, Schwalbe H.  2013.  MOTOR: Model assisted Software for NMR Structure Determination. Proteins. 81:2007-2022.
Hiruma Y, Hass MAS, Kikui Y, Liu W-M, Ölmez B, Skinner SP, Blok A, Kloosterman A, Koteishi H, Löhr F et al..  2013.  The Structure of the Cytochrome P450cam-Putidaredoxin Complex Determined by Paramagnetic NMR Spectroscopy and Crystallography. J. Mol. Biol.. 425:4353-4365.
2012
Saxena K, Dutta A, Klein-Seetharaman J, Schwalbe H.  2012.  Isotope labeling in insect cells. Methods Mol Biol.. 831:37-54..
2008
Nasiri HR, Bolte M, Schwalbe H.  2008.  Electrochemical and crystal structural analysis of alpha- and dehydro-alpha-lapachones.. Nat Prod Res. 22:1225–1230. Abstract
2007
Haber-Pohlmeier S, Abarca-Heidemann K, Körschen HG, Dhiman KH, Heberle J, Schwalbe H, Klein-Seetharaman J, Kaupp UB, Pohlmeier A.  2007.  Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment.. Biophys J. 92:3207–3214. Abstract
2006
Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dötsch V, Engelke F, Folkers GE et al..  2006.  NMR in the SPINE Structural Proteomics project.. Acta Crystallogr D Biol Crystallogr. 62:1150–1161. Abstract
2002
Klein-Seetharaman J, Reeves PJ, Loewen MC, Getmanova EV, Chung J, Schwalbe H, Wright PE, Khorana HG.  2002.  Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence.. Proc Natl Acad Sci U S A. 99:3452–3457. Abstract
Griesinger C, Hennig M, Marino J, Reif B, Richter C, Schwalbe H.  2002.  Methods for the Determination of Torsion Angle Restraints in Biomacromolecules. Modern Techniques in Protein NMR. :259-367.
2001
Duchardt E, Richter C, Reif B, Glaser SJ, Engels JW, Griesinger C, Schwalbe H.  2001.  Measurement of 2J(H,C)- and 3J(H,C)-coupling constants by alpha/beta selective HC(C)H-TOCSY.. J Biomol NMR. 21:117–126. Abstract
Peti W, Smith LJ, Redfield C, Schwalbe H.  2001.  Chemical shifts in denatured proteins: resonance assignments for denatured ubiquitin and comparisons with other denatured proteins.. J Biomol NMR. 19:153–165. Abstract
Smith CK, Wöhnert J, Sauer RT, Schwalbe H.  2001.  Assignments of the 1H,13C, and 15N resonances of the substrate-binding SSD domain from Lon protease.. J Biomol NMR. 21:387–388.
Rivas MJC, Schwalbe H, Lippard SJ.  2001.  Interchain hydrogen-bonding interactions may facilitate translocation of K+ ions across the potassium channel selectivity filter, as suggested by synthetic modeling chemistry.. Proc Natl Acad Sci U S A. 98:9478–9483. Abstract
Schwalbe H, Grimshaw SB, Spencer A, Buck M, Boyd J, Dobson CM, Redfield C, Smith LJ.  2001.  A refined solution structure of hen lysozyme determined using residual dipolar coupling data.. Protein Sci. 10:677–688. Abstract
Loewen MC, Klein-Seetharaman J, Getmanova EV, Reeves PJ, Schwalbe H, Khorana HG.  2001.  Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin.. Proc Natl Acad Sci U S A. 98:4888–4892. Abstract
Schwalbe H, Carlomagno T, Hennig M, Junker J, Reif B, Richter C, Griesinger C.  2001.  Cross-correlated relaxation for measurement of angles between tensorial interactions.. Methods Enzymol. 338:35–81.
1999
Elshorst B, Hennig M, Försterling H, Diener A, Maurer M, Schulte P, Schwalbe H, Griesinger C, Krebs J, Schmid H et al..  1999.  NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump.. Biochemistry. 38:12320–12332. Abstract
Richter C, Griesinger C, Felli I, Cole PT, Varani G, Schwalbe H.  1999.  Determination of sugar conformation in large RNA oligonucleotides from analysis of dipole-dipole cross correlated relaxation by solution NMR spectroscopy.. J Biomol NMR. 15:241–250. Abstract
Hennig M, Bermel W, Spencer A, Dobson CM, Smith LJ, Schwalbe H.  1999.  Side-chain conformations in an unfolded protein: chi1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy.. J Mol Biol. 288:705–723. Abstract
1998
Carlomagno T, Schwalbe H, Rexroth A, Sorensen OW, Griesinger C.  1998.  New methylene specific experiments for the measurement of scalar spin-spin coupling constants between protons attached to 13C.. J Magn Reson. 135:216–226. Abstract
1997
Schwalbe H, Fiebig KM, Buck M, Jones JA, Grimshaw SB, Spencer A, Glaser SJ, Smith LJ, Dobson CM.  1997.  Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea.. Biochemistry. 36:8977–8991. Abstract
1996
Smith LJ, Bolin KA, Schwalbe H, MacArthur MW, Thornton JM, Dobson CM.  1996.  Analysis of main chain torsion angles in proteins: prediction of NMR coupling constants for native and random coil conformations.. J Mol Biol. 255:494–506. Abstract
Glaser SJ, Schwalbe H, Marino JP, Griesinger C.  1996.  Directed TOCSY, a method for selection of directed correlations by optimal combinations of isotropic and longitudinal mixing.. J Magn Reson B. 112:160–180. Abstract
Buck M, Schwalbe H, Dobson CM.  1996.  Main-chain dynamics of a partially folded protein: 15N NMR relaxation measurements of hen egg white lysozyme denatured in trifluoroethanol.. J Mol Biol. 257:669–683. Abstract
Marino JP, Schwalbe H, Glaser SJ, Griesinger C.  1996.  Determination of γ and Stereospecific Assignment of H5‘ Protons by Measurement of 2J and 3J Coupling Constants in Uniformly 13C Labeled RNA. J Am Chem Soc. 118(18):4388-4395. Abstract
1995
Buck M, Schwalbe H, Dobson CM.  1995.  Characterization of conformational preferences in a partly folded protein by heteronuclear NMR spectroscopy: assignment and secondary structure analysis of hen egg-white lysozyme in trifluoroethanol.. Biochemistry. 34:13219–13232. Abstract
Marino JP, Schwalbe H, Anklin C, Bermel W, Crothers DM, Griesinger C.  1995.  Sequential correlation of anomeric ribose protons and intervening phosphorus in RNA oligonucleotides by a 1H, 13C, 31P triple resonance experiment: HCP-CCH-TOCSY.. J Biomol NMR. 5:87–92. Abstract
Rexroth A, Szalma S, Weisemann R, Bermel W, Schwalbe H, Griesinger C.  1995.  Determination of 3J(HNi,C'i) coupling constants in proteins with the C′-FIDS method. Journal of Biomolecular NMR. 6(3):237-244. Abstract
Rexroth A, Schmidt P, Szalma S, Geppert T, Schwalbe H, Griesinger C.  1995.  New principle for the determination of coupling constants that largely suppresses differential relaxation effects. J Am Chem Soc. 117(41):10389-10390.
1994
Schwalbe H, Marino JP, King GC, Wechselberger R, Bermel W, Griesinger C.  1994.  Determination of a complete set of coupling constants in 13C-labeled oligonucleotides.. J Biomol NMR. 4:631–644. Abstract
Karimi-Nejad Y, Schmidt JM, Rüterjans H, Schwalbe H, Greisinger C.  1994.  Conformation of valine side chains in ribonuclease T1 determined by NMR studies of homonuclear and heteronuclear 3J coupling constants.. Biochemistry. 33:5481–5492. Abstract