Publications

Found 184 results

2017
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J et al..  2017.  The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol..
Schwalbe H.  2017.  New 1.2 GHz NMR spectrometers - new horizons? Angew. Chem. Int. Ed.. 56:10252-10253.
Helmling C, Wacker A, Wolfinger MT, Hofacker IL, Hengesbach M, Fürtig B, Schwalbe H.  2017.  NMR structural profiling of transcriptional intermediates reveals riboswitch regulation by metastable RNA conformations. J. Am. Chem. Soc.. 139(7):2647-2656.
DiGuiseppi D, Milorey B, Lewis G, Kubatova N, Farrell S, Schwalbe H, Schweitzer-Stenner R.  2017.  Probing the Conformation Dependent Preferential Binding of Ethanol to Cationic Glycylalanylglycine in Water/Ethanol by Vibrational and NMR Spectroscopy. J. Chem. Phys.. 121(23):5744-5758.
Hutchison M, Schwalbe H.  2017.  Protein misfolding. Modern Magnetic Resonance: 2nd edition.
Cai X, Shi YM, Pöhlmann N, Revermann O, Bahner I, Pidot SJ, Wesche F, Lackner H, Büchel C, Kaiser M et al..  2017.  Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66.. Angew. Chem. Intl. Ed.. 56:4945-4949.
Bessi I, Wirmer-Bartoschek J, Dash J, Schwalbe H.  2017.  Targeting G-quadruplex with small molecules: an NMR view. Modern Magnetic Resonance: 2nd edition.
Pinter G, Schwalbe H.  2017.  Unprecedented carbon signal enhancement in liquid-state NMR spectroscopy. Angew, Chem. Int. Ed. . 56(29):8332-8334.
2016
Sochor F, Silvers R, Müller D, Richter C, Fürtig B, Schwalbe H.  2016.  19F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy.. J Biomol NMR. 64(1):63-74.
Grothe J, Krysciak D, Petersen K, Güllert S, Förstner KU, Krishnan HB, Schwalbe H, Kubatova N, Streit W.  2016.  The Absence of the N-acyl-homoserine-lactone Autoinducer Synthase Genes traI and ngrI Increases the Copy Number of the Symbiotic Plasmid in Sinorhizobium fredii NGR234. Front. Microbiol.. 7:1858.
Stellos K, Gatsiou A, Stamatelopoulos K, Matic LP, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F et al..  2016.  Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.. Nat. Medicine. 22:1140-1150.
Nasiri AH, Saxena K, Bats JW, Nasiri HR, Schwalbe H.  2016.  Biophysical investigation and conformational analysis of p38α kinase inhibitor doramapimod and its analogues. MedChemCom. 7:1421-1428.
Hahn J, Thalmann S, Migur A, von Boeselager FR, Kubatova N, Kubareva E, Schwalbe H, Evguenieva-Hackenberg E.  2016.  Conserved small mRNA with an unique, extended Shine-Dalgarno sequence. RNA Biol..
Fürtig B, Schnieders R, Richter C, Zetzsche H, Keyhani S, Helmling C, Kovacs H, Schwalbe H.  2016.  Direct 13C-detected NMR Experiments for Mapping and Characterization of Hydrogen Bonds in RNA. J. Biomol. NMR. 64(3):207-21.
Kumar PY, Saha P, Saha D, Bessi I, Schwalbe H, Chowdhurz S, Dash J.  2016.  Fluorescent Dansyl-guanosine Conjugates That Bind c-MYC Promoter G-quadruplex and Down-regulate c-MYC Expression. Chembiochem. 17(5):388-93.
Kaushik M, Bahrenberg T, Can TV, Caporini MA, Silvers R, Heiliger J, Smith AA, Schwalbe H, Griffin RG, Corzilius B.  2016.  Gd(iii) and Mn(ii) complexes for dynamic nuclear polarization: small molecular chelate polarizing agents and applications with site-directed spin labeling of proteins.. Phys Chem Chem Phys. 18:27205-27218.
Daube D, Aladin V, Heiliger J, Wittmann J, Barthelmes D, Schwalbe H, Corzilius B.  2016.  Heteronuclear cross-relaxation under solid-state dynamic nuclear polarization. J. Am. Chem. Soc.. 138(51):16572-16575.
Henker J, Wirmer-Bartoschek J, Bendel LE, Xiang YG, Fu C, Harms K, Schwalbe H, Meggers E.  2016.  Progress in the synthesis and bioactivity of hexacoordinate silicon (IV) complexes. European Journal of Inorganic Chemistry. 32(5161-5170)
Zhu W, Silvers R, Schwalbe H, Keiderling T.  2016.  Reduced and mutant lysozyme refolding with lipid vesicles. Model study of impact of disulfides on equilibria and dynamics.. Biochim Biophys Acta. 1864(9):1083-92.
Debnath M, Ghosh S, Panda D, Bessi I, Schwalbe H, Bhattacharyya K, Dash J.  2016.  Small Molecule Regulated Dynamic Structural changes of Human G-quadruplexes. Chemical Science. 7:3279-3285.
Heering J, Jonker HRA, Löhr F, Schwalbe H, Dötsch V.  2016.  Structural investigations oft he p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci.. 25(2):410-22.
Chauhan A, Paul R, Debnath M, Bessi I, Mandal S, Schwalbe H, Dash J.  2016.  Synthesis of Fluorescent Binaphthyl Amines That Bind c-MYC G-Quadruplex DNA and Repress c-MYC Expression.. J Med Chem. 59:7275-81.
Wirmer-Bartoschek J, Schwalbe H.  2016.  Understanding how DNA enzymes work. Angew. Chem. Int. Ed.. 55(18):5376-7.
2015
Nasiri HR, Ferner J, Tükek C, Krishnathas R, Schwalbe H.  2015.  A concise one-step synthesis of primin and iso-primin. Tetrahedron Lett.. 56:2231-2233.
Buhr F, Kohl-Landgraf J, tom Dieck S, Hanus C, Chatterjee D, Hegelein A, Schuman EM, Wachtveitl J, Schwalbe H.  2015.  Design of photocaged puromycin for nascent polypeptide release and spatiotemporal monitoring of translation. Angew. Chem. Intl. Ed.. 54:3717-21.
Silvers R, Keller H, Schwalbe H, Hengesbach M.  2015.  Differential Scanning Fluorimetry for Monitoring RNA Stability. ChemBioChem. 16:1109–1114.
Barthelmes D, Gränz M, Barthelmes K, Allen KN, Imperiali B, Prisner T, Schwalbe H.  2015.  Encoded Loop-Lanthanide-Binding Tags for Long-Range Distance Measurements in Proteins by NMR and EPR Spectroscopy. J. Biomol. NMR. 63(3):275-82.
Baldus-Becker J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H et al..  2015.  Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci USA. 112(32):9896-901.
Ardenkjaer-Larsen J-H, Boebinger GS, Comment A, Duckett S, Edison A, Engelke F, Griesinger C, Griffin RG, Hilty C, Maeda H et al..  2015.  Facing and Overcoming Biomolecular NMR’s sensitivity challenges. Angew. Chem. Intl. Ed.. 54:9162-85.
Göbel M, Schwalbe H.  2015.  Gerhard Quinkert (1927-2015). Angew, Chem. Int. Ed. . 54:8597.
Kudlinzki D, Linhard VL, Saxena K, Sreeramulu S, Gande S, Schieborr U, Dreyer M, Schwalbe H.  2015.  High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.. Acta Crystallogr F Struct Biol Commun.. 71:1088-93.
D.Chatterjee, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H.  2015.  Influence of arrestin on the photodecay of bovine rhodopsin. Angew, Chem. Int. Ed.. 54:13555-13560.
Rehbein P, Schwalbe H.  2015.  Integrated protocol for reliable and fast quantification and documentation of electrophoresis gels. Protein Expr Purif.. 2015(110):1-6.
Zickermann V, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Brandt U.  2015.  Mechanistic insight from the crystal structure of mitochondrial complex I. Science. 347(6217):44-49.
Fürtig B, Nozinovic S, Reining A, Schwalbe H.  2015.  Multiple conformational states of riboswitches fine-tune gene regulation. Curr. Opin. Struct. Biol.. 30:112-124.
Scharow A, Raab M, Saxena K, Sreeramulu S, Kudlinzki D, Gande S, Dötsch C, Kurunci-Csacsko E, Kläger S, Küster B et al..  2015.  Optimized Plk1 PBD inhibitors based on Poloxin induce mitotic arrest and apoptosis in tumor cells. ACS Chemical Biology. 10(11):2570-9.
Saxena K, Schwalbe H.  2015.  The role of NMR in target identification and validation for pharmaceutical R&D. 4:305-314..
Bruns N, Collisi W, Bernecker S, Stadler M, Richter C, Schwalbe H, Kalesse M.  2015.  Spirangien Derivatives from the Myxobacterium Sorangium cellulosum: Isolation, Structure Elucidation, and Biological Activity. European Journal of Organic Chemistry. 4:847-857.
Schimming O, Challinor VL, Tobias NJ, Adihou H, Grün P, Pöschel L, Richter C, Schwalbe H, Bode HB.  2015.  Structure, Biosynthesis, and Occurence of Bacterial Pyrrolizidine Alkaloids. Angew. Chem. Intl. Ed.. 54:12702-5.
2014
Schilder J, Löhr F, Schwalbe H, Ubbink M.  2014.  The cytochrome c peroxidase and cytochrome c encounter complex: The other side of the story; see also: corrigendum: FEBS Lett. (2015) 589, 2169.. FEBS Lett.. 588(10):1873-8.
Nozinovic S, Reining A, Kim Y-B, Noeske J, Schlepckow K, Wöhnert J, Schwalbe H.  2014.  The importance of helix P1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain. RNA Biology. 11(5):655-666.
2013
Nasiri H, Madej G, Panisch R, Bats J, Lafontaine M, Lancaster CR, Schwalbe H.  2013.  Design, Synthesis and Biological Testing of Novel Naphthoquinones as Substrate-Based Inhibitors of the Quinol:Fumarate Reductase from Wolinella succinogenes.. J. Med. Chem..
Schweitzer-Stenner R, Hagarmann A, Toal S, Mathieu D, Schwalbe H.  2013.  Disorder and order in unfolded and disordered peptides and proteins: A view derived from tripeptide conformational analysis. I. Tripeptides with long and predominantly hydrophobic side chains.. Proteins. 81:955-967.
Rybka K, Toal SE, D.J.Verbaro, Mathieu D, Schwalbe H, Schweizer-Stenner R.  2013.  Disorder and order in unfolded and disordered peptides and proteins: A view derived from tripeptide conformational analysis. II. tripeptides with short side chains populating asx and β-type like turn conformations.. Proteins. 81:968-983.
Kumar YP, Bhowmik S, Das RN, Bessi I, Paladhi S, Ghosh R, Schwalbe H, Dash J.  2013.  A fluorescent guanosine dinucleoside as a selective switch-on sensor for c-myc G-quadruplex DNA with potent anticancer activities. Chemistry - A European Journal. 19(35):11502-6.
Nielsen G, Jonker HRA, Vajpaj N, Grzesiek S, Schwalbe H.  2013.  Kinase in motion: insights into the dynamic nature of p38alpha by high pressure NMR spectroscopic studies.. ChemBioChem. 14:1799-1806.
Schieborr U, Sreeramulu S, Elshorst B, Maurer M, Saxena K, Kudlinzki D, Gande S, Schwalbe H.  2013.  MOTOR: Model assisted Software for NMR Structure Determination. Proteins. 81:2007-2022.
Hiruma Y, Hass MAS, Kikui Y, Liu W-M, Ölmez B, Skinner SP, Blok A, Kloosterman A, Koteishi H, Löhr F et al..  2013.  The Structure of the Cytochrome P450cam-Putidaredoxin Complex Determined by Paramagnetic NMR Spectroscopy and Crystallography. J. Mol. Biol.. 425:4353-4365.
2012
Saxena K, Dutta A, Klein-Seetharaman J, Schwalbe H.  2012.  Isotope labeling in insect cells. Methods Mol Biol.. 831:37-54..
2008
Nasiri HR, Bolte M, Schwalbe H.  2008.  Electrochemical and crystal structural analysis of alpha- and dehydro-alpha-lapachones.. Nat Prod Res. 22:1225–1230. Abstract