Publications

Found 213 results

2019
Reese M, George C, Yang C, Jawla S, Grün TJ, Schwalbe H, Redfield C, Temkin RJ, Griffin RG.  2019.  Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz. J. Magn. Reson.. 307:106573.
Cetiner EC, Jonker HRA, Helmling C, Gophane DB, Grünewald C, Sigurdsson ST, Schwalbe H.  2019.  Paramagnetic-Iterative Relaxation Matrix Approach – Extracting PRE-Restraints from NOESY Spectra for 3D Structure Elucidation of Biomolecules. J. Biomol. NMR. 73(12):699-712.
Kubatova N, Jonker HRA, Saxena K, Richter C, Vogel V, Schreiber S, Marchfelder A, Schwalbe H.  2019.  Solution structure and dynamics of the small protein HVO_2922 from Haloferax volcanii. ChemBioChem. 21(1-2):149-156.
2018
Dutta D, Debnanth M, Müller D, Paul R, Das T, Bessi I, Schwalbe H, Dash J.  2018.  Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex. Nucl. Acids Res.. 46:5355-5365.
Niesteruk A, Jonker HRA, Richter C, Linhardt V, Sreeramulu S, Schwalbe H.  2018.  The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture. J. Biol. Chem.. 293 :11823-11836.
Coutinho ID, Henning LMM, Döpp SA, Mepomuceno A, Morales LAC, Marcolino-Gomes J, Richter C, Schwalbe H, Colnago LA.  2018.  Flooded soybean metabolomic analysis reveals important primary and secondary metabolites involved in the hypoxia stress response and tolerance. Environmental and Experimental Biology. 153:176-187.
Shi YM, Richter C, Challinor VL, Grün P, GirelaDelRio A, Kaiser M, SChüffler A, Piepenbring M, Schwalbe H, Bode HB.  2018.  Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus. Org Lett. 20:1563-1567.
Maiti S, Saha P, Das T, Bessi I, Schwalbe H, Dash J.  2018.  Human Telomeric G-quadruplex Selective Fluoro-isoquinolines Induce Apoptosis in Cancer Cells. Bioconjugate Chemistry. 29(4):1141-1154.
Coutinho ID, Henning LMM, Döpp SA, Nepomuceno A, Moraes LAC, Marcolino-Gomes J, Richter C, Schwalbe H, Colnago LA.  2018.  Identification of primary and secondary metabolites and transcriptome profile of soybean tissues during different stages of hypoxia. Data Brief. 21:1089-1100.
Rehbein P, Schwalbe H.  2018.  Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions. Protein Expr Purif. 150:53-60.
Muthukumar Y, Münkemer J, Mathieu D, Richter C, Schwalbe H, Steinmetz H, Kessler W, Reichelt J, Beutling U, Frank R et al..  2018.  Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria. PLOS One. 13:e0201605.
Helmling C, Klötzner D, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H.  2018.  Life times of metastable states guide regulatory signaling in transcriptional riboswitches. Nat. Commun.. 9:944.
Raab M, Sanhaji M, Pietsch L, Béquignon I, Herbrand AK, Süß E, Gande SL, Caspar B, Kudlinzki D, Saxena K et al..  2018.  Modulation of the Allosteric Communication between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds. ACS Chem Biol. 13:1921-1931.
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J et al..  2018.  The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.. Nat. Chem. Biol.. 14:284-290.
Elamri I, Heumüller M, Herzig LM, Stirnal E, Wachtveitl J, Schuman E, Schwalbe H.  2018.  A new photocaged puromycin for an efficient labelling of newly translated proteins in living neurons. ChemBioChem. 19:2358-2464.
Wienen-Schmidt B, Wulsdorf T, Jonker HRA, Saxena K, Kudlinzki D, Linhard V, Sreeramulu S, Heine A, Schwalbe H, Klebe G.  2018.  On the implication of water on fragment-to-ligand growth in kinase binding thermodynamics. ChemMedChem. 13:1988-1996.
Debnath M, Ghosh S, Panda D, Bessi I, Schwalbe H, Bhattacharyya K, Dash J.  2018.  Small molecule regulated dynamic structural changes of human G-quadruplexes. Chem. Sci.. 7:3279-3285.
Kappert F, Sreeramulu S, Jonker HRA, Richter C, Rogov VV, Proschak E, Hargittay B, Saxena K, Schwalbe H.  2018.  Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor. Chemistry - A European Journal. 24:7861-7865.
Niesteruk A, Hutchison M, Sreeramulu S, Jonker HRA, Richter C, Abele R, Bock C, Schwalbe H.  2018.  Structural characterization of the Intrinsically Disordered Domain (IDD) of Mycobacterium tuberculosis Protein Tyrosine Kinase A (PtkA). FEBS Lett.. 592(7):1233-1245.
Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O et al..  2018.  Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat. Commun..
2017
Heinzlmeir S, Lohse J, Treiber T, Kudlinzki D, Linhardt V, Gande SL, Sreeramulu S, Saxena K, Liu X, Wilhelm M et al..  2017.  Chemoproteomics-aided medicinal chemistry for the discovery of EPHA2 inhibitors. ChemMedChem. 12(12):999-1011.
Barthelmes D, Barthelmes K, Schnorr K, Jonker HRA, Bodmer B, Allen KN, Imperiali B, Schwalbe H.  2017.  Conformational dynamics and alignment properties of lopp Lanthanide-Binding-Tags (LBTs) studied in Interleukin-1beta. J. Biomol. NMR. 68(3):187-194.
Schnieders R, Richter C, Warhaut S, de Jesus V, Keyhani S, Duchardt-Ferner E, Keller H, Wöhnert J, Kuhn LT, Breeze AL et al..  2017.  Evaluation of 15N-detected H-N correlation experiments on increasingly large RNAs. J. Biomol. NMR. 69:31-44.
Schnorr K, Gophane DB, Helmling C, Cetiner E, Pasemann K, Fürtig B, Wacker A, Qureshi NS, Gränz M, Barthelmes D et al..  2017.  Impact of spin label rigidity on extent and accuracy of distance information from PRE data. J. Biomol. NMR. 68(1):53-63.
Nasiri HR, Hohmann K, Hatemler M, Schwalbe H.  2017.  In vitro production of reactive oxygen species (ROS) by sampangine. Med. Chem. Res.. 26:1170-1175.
Lannes L, Young P, Richter C, Morgner N, Schwalbe H.  2017.  Interaction of the N-Terminal Tandem Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA Sequence. ChemBioChem. 18(20):2033-2044.
Kim YB, Wacker A, von Laer K, Rogov V, Suess B, Schwalbe H.  2017.  Ligand binding to 2’-deoxyguanosine sensing riboswitch in metabolic context. Nucl. Acids Res.. 45(9):5375-5386.
Warhaut S, Mertinkus KR, Höllthaler P:, Fürtig B, Heilemann M, Hengesbach M, Schwalbe H.  2017.  Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy. Nucl. Acids Res.. 45:5512-5522.
Liu Y, Sharp JS, Do DH, Kahn RA, Schwalbe H, Buhr F, Prestegard J.  2017.  Mistakes in translation: Reflections on mechanism.. PLoS One. 12(6 ):e0180566.
Joedicke L, Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J et al..  2017.  The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol..
Schwalbe H.  2017.  New 1.2 GHz NMR spectrometers - new horizons? Angew. Chem. Int. Ed.. 56:10252-10253.
Helmling C, Wacker A, Wolfinger MT, Hofacker IL, Hengesbach M, Fürtig B, Schwalbe H.  2017.  NMR structural profiling of transcriptional intermediates reveals riboswitch regulation by metastable RNA conformations. J. Am. Chem. Soc.. 139(7):2647-2656.
DiGuiseppi D, Milorey B, Lewis G, Kubatova N, Farrell S, Schwalbe H, Schweitzer-Stenner R.  2017.  Probing the Conformation Dependent Preferential Binding of Ethanol to Cationic Glycylalanylglycine in Water/Ethanol by Vibrational and NMR Spectroscopy. J. Chem. Phys.. 121(23):5744-5758.
Hutchison M, Schwalbe H.  2017.  Protein misfolding. Modern Magnetic Resonance: 2nd edition.
Cai X, Shi YM, Pöhlmann N, Revermann O, Bahner I, Pidot SJ, Wesche F, Lackner H, Büchel C, Kaiser M et al..  2017.  Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66.. Angew. Chem. Intl. Ed.. 56:4945-4949.
Bessi I, Wirmer-Bartoschek J, Dash J, Schwalbe H.  2017.  Targeting G-quadruplex with small molecules: an NMR view. Modern Magnetic Resonance: 2nd edition.
Pinter G, Schwalbe H.  2017.  Unprecedented carbon signal enhancement in liquid-state NMR spectroscopy. Angew, Chem. Int. Ed. . 56(29):8332-8334.
2016
Sochor F, Silvers R, Müller D, Richter C, Fürtig B, Schwalbe H.  2016.  19F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy.. J Biomol NMR. 64(1):63-74.
Grothe J, Krysciak D, Petersen K, Güllert S, Förstner KU, Krishnan HB, Schwalbe H, Kubatova N, Streit W.  2016.  The Absence of the N-acyl-homoserine-lactone Autoinducer Synthase Genes traI and ngrI Increases the Copy Number of the Symbiotic Plasmid in Sinorhizobium fredii NGR234. Front. Microbiol.. 7:1858.
Stellos K, Gatsiou A, Stamatelopoulos K, Matic LP, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F et al..  2016.  Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.. Nat. Medicine. 22:1140-1150.
Nasiri AH, Saxena K, Bats JW, Nasiri HR, Schwalbe H.  2016.  Biophysical investigation and conformational analysis of p38α kinase inhibitor doramapimod and its analogues. MedChemCom. 7:1421-1428.
Hahn J, Thalmann S, Migur A, von Boeselager FR, Kubatova N, Kubareva E, Schwalbe H, Evguenieva-Hackenberg E.  2016.  Conserved small mRNA with an unique, extended Shine-Dalgarno sequence. RNA Biol..
Fürtig B, Schnieders R, Richter C, Zetzsche H, Keyhani S, Helmling C, Kovacs H, Schwalbe H.  2016.  Direct 13C-detected NMR Experiments for Mapping and Characterization of Hydrogen Bonds in RNA. J. Biomol. NMR. 64(3):207-21.
Kumar PY, Saha P, Saha D, Bessi I, Schwalbe H, Chowdhurz S, Dash J.  2016.  Fluorescent Dansyl-guanosine Conjugates That Bind c-MYC Promoter G-quadruplex and Down-regulate c-MYC Expression. Chembiochem. 17(5):388-93.
Kaushik M, Bahrenberg T, Can TV, Caporini MA, Silvers R, Heiliger J, Smith AA, Schwalbe H, Griffin RG, Corzilius B.  2016.  Gd(iii) and Mn(ii) complexes for dynamic nuclear polarization: small molecular chelate polarizing agents and applications with site-directed spin labeling of proteins.. Phys Chem Chem Phys. 18:27205-27218.
Daube D, Aladin V, Heiliger J, Wittmann J, Barthelmes D, Schwalbe H, Corzilius B.  2016.  Heteronuclear cross-relaxation under solid-state dynamic nuclear polarization. J. Am. Chem. Soc.. 138(51):16572-16575.
Henker J, Wirmer-Bartoschek J, Bendel LE, Xiang YG, Fu C, Harms K, Schwalbe H, Meggers E.  2016.  Progress in the synthesis and bioactivity of hexacoordinate silicon (IV) complexes. European Journal of Inorganic Chemistry. 32(5161-5170)
Zhu W, Silvers R, Schwalbe H, Keiderling T.  2016.  Reduced and mutant lysozyme refolding with lipid vesicles. Model study of impact of disulfides on equilibria and dynamics.. Biochim Biophys Acta. 1864(9):1083-92.
Debnath M, Ghosh S, Panda D, Bessi I, Schwalbe H, Bhattacharyya K, Dash J.  2016.  Small Molecule Regulated Dynamic Structural changes of Human G-quadruplexes. Chemical Science. 7:3279-3285.
Heering J, Jonker HRA, Löhr F, Schwalbe H, Dötsch V.  2016.  Structural investigations oft he p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci.. 25(2):410-22.